Transition metal promoted Brook rearrangement and its related reactions

IF 2.1 3区化学 Q2 CHEMISTRY, ORGANIC

Tetrahedron Pub Date : 2024-10-31 DOI:10.1016/j.tet.2024.134351

Fazhou Yang, Jinbao Wang, Yujie Dong, Nianci Zhang, Cheng Zhang

引用次数: 0

Abstract

The Brook Rearrangement holds significant applications in organic synthesis and has been investigated extensively in past decades. Among the various types of Brook rearrangements, catalytic versions have gained increased attention from the chemical community due to their superior control over stereoselectivity and high reaction efficiency. This review provides a comprehensive summary of recent examples of transition metal-promoted Brook rearrangement and related reactions. It encompasses copper-catalyzed migration of a silyl or boryl group, which represents the most intensively studied reactions, along with zinc-promoted reactions and other transition metal-catalyzed reactions. The substrate scope and reaction mechanisms of these examples are meticulously detailed and analyzed.

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过渡金属促进布鲁克重排及其相关反应

布鲁克重排在有机合成中有着重要的应用，在过去的几十年中得到了广泛的研究。在各种类型的布鲁克重排反应中，催化型布鲁克重排反应因其出色的立体选择性控制和较高的反应效率而日益受到化学界的关注。本综述全面总结了过渡金属促进的布鲁克重排及相关反应的最新实例。它包括铜催化的硅烷基或硼烷基迁移（这是研究最深入的反应），以及锌催化反应和其他过渡金属催化反应。对这些实例的底物范围和反应机理进行了细致入微的分析。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Tetrahedron 化学-有机化学

CiteScore

3.90

自引率

4.80%

发文量

439

审稿时长

34 days

期刊介绍： Tetrahedron publishes full accounts of research having outstanding significance in the broad field of organic chemistry and its related disciplines, such as organic materials and bio-organic chemistry. Regular papers in Tetrahedron are expected to represent detailed accounts of an original study having substantially greater scope and details than that found in a communication, as published in Tetrahedron Letters. Tetrahedron also publishes thematic collections of papers as special issues and ''Reports'', commissioned in-depth reviews providing a comprehensive overview of a research area.