Voltammetric detection of chlorogenic acid by Poly(3,4-ethylene-dioxythiophene) electrodes

IF 4.1 3区化学 Q1 CHEMISTRY, ANALYTICAL

Journal of Electroanalytical Chemistry Pub Date : 2024-10-29 DOI:10.1016/j.jelechem.2024.118736

Wei-Li Shih, Lin-Chi Chen

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Abstract

This work aims at developing selective detection of chlorogenic acid (CGA), a critical phenolic acid related to the antioxidant level and taste of coffee, by a pristine poly(3,4-ethylenedioxythiophene) (PEDOT) electrode. The electrochemical oxidation of CGA on two types of PEDOT films, electrodeposited in aqueous (water, aq-PEDOT) and non-aqueous solvents (acetonitrile, ACN-PEDOT), were systematically studied and compared. Aq-PEDOT film showed a linear response for CGA in a range from 1.5 µM to 2.5 mM and a sensitivity of 0.33 mA/cm²⋅mM; ACN-PEDOT film showed a non-linear response with residual CGA. For repeated sensing purposes, we chose aq-PEDOT for the CGA sensor demonstration. Although cross-sensitivity with gallic acid (GA) and caffeic acid (CA) at 0.35 V was observed due to the shared catechol structure, selectivity for CGA determination against vanillin (VAN), guaiacol (GUA), theobromine (THB), theophylline (THP), quinic acid (QA), and caffeine (CAF) was confirmed. The distinct sensing behavior of the PEDOT films was further investigated: aq-PEDOT had a relatively flat surface and obeyed diffusion-controlled kinetics for CGA electro-oxidation. In contrast, ACN-PEDOT had a rougher coral-like morphology and strong adsorption characteristics. The measurements in real coffee samples by aq-PEDOT were also demonstrated with the interference from CA compensated. In brief, this study proves the niches and provides in-depth electrochemical kinetics for voltammetric CGA sensing using the PEDOT films prepared in aqueous and non-aqueous environments.

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聚（3,4-乙烯二氧噻吩）电极对绿原酸的伏安检测

这项研究旨在开发一种原始聚（3,4-亚乙二氧基噻吩）（PEDOT）电极，用于选择性检测绿原酸（CGA），这是一种与咖啡抗氧化水平和口感有关的重要酚酸。我们系统地研究并比较了在水溶液（水，aq-PEDOT）和非水溶液（乙腈，ACN-PEDOT）中电沉积的两种 PEDOT 薄膜上 CGA 的电化学氧化过程。在 1.5 µM 至 2.5 mM 范围内，水溶液-PEDOT 薄膜对 CGA 呈线性响应，灵敏度为 0.33 mA/cm2⋅mM；而 ACN-PEDOT 薄膜对残留的 CGA 呈非线性响应。出于重复传感的目的，我们选择了 aq-PEDOT 来演示 CGA 传感器。虽然由于共享的儿茶酚结构，在 0.35 V 的电压下与没食子酸（GA）和咖啡酸（CA）出现了交叉敏感性，但我们证实了 CGA 检测对香兰素（VAN）、愈创木酚（GUA）、可可碱（THB）、茶碱（THP）、奎宁酸（QA）和咖啡因（CAF）的选择性。我们进一步研究了 PEDOT 薄膜的不同传感行为：Aq-PEDOT 具有相对平坦的表面，在 CGA 电氧化过程中服从扩散控制动力学。相比之下，ACN-PEDOT 具有更粗糙的珊瑚状形貌和强大的吸附特性。使用 aq-PEDOT 在真实咖啡样品中进行的测量也证明，CA 的干扰得到了补偿。简而言之，本研究证明了在水和非水环境中使用制备的 PEDOT 薄膜进行伏安法 CGA 传感的优势，并提供了深入的电化学动力学。

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来源期刊

Journal of Electroanalytical Chemistry 化学-电化学

CiteScore

7.80

自引率

6.70%

发文量

912

审稿时长

2.4 months

期刊介绍： The Journal of Electroanalytical Chemistry is the foremost international journal devoted to the interdisciplinary subject of electrochemistry in all its aspects, theoretical as well as applied. Electrochemistry is a wide ranging area that is in a state of continuous evolution. Rather than compiling a long list of topics covered by the Journal, the editors would like to draw particular attention to the key issues of novelty, topicality and quality. Papers should present new and interesting electrochemical science in a way that is accessible to the reader. The presentation and discussion should be at a level that is consistent with the international status of the Journal. Reports describing the application of well-established techniques to problems that are essentially technical will not be accepted. Similarly, papers that report observations but fail to provide adequate interpretation will be rejected by the Editors. Papers dealing with technical electrochemistry should be submitted to other specialist journals unless the authors can show that their work provides substantially new insights into electrochemical processes.