Advances in arthropod-inspired bionic materials for wound healing

IF 8.7 1区 医学 Q1 ENGINEERING, BIOMEDICAL
Yuchen Li , Jiaming Cui , Di Xiao , Bixuan Cao , Jing Wei , Qian Wang , Junwei Zong , Jinwu Wang , Mingzhi Song
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引用次数: 0

Abstract

Arthropods contain lots of valuable bionic information from the composition to the special structure of the body. In particular, the rapid self-healing ability and antibacterial properties are amazing. Biomimetic materials for arthropods have been helpful methods for wound management. Here, we have identified four major dimensions needed to create biomimetic materials for arthropods, including ingredient, behavior, structure and internal reaction. According to different dimensions, we classify and introduce the reported arthropod biomimetic materials. Antibacterial, hemostatic and healing promotion are the main functions of the active compositions of arthropods developed by humans, and most of them play a drug effect. We believe that an ideal biomimetic material of arthropod should have the effect on promoting wound healing through the advantages of structure and composition. The special macroscopic and microscopic structure of the epidermis may provide good mechanical support for biomimetic materials. The drug release regularity in the bionic materials can be referred to the aggressive and secretory behavior of arthropods. The synthesis of substances in arthropods is also noteworthy, and we can learn these special reactions to complete the fast preparation of materials. Arthropod-inspired bionic materials have broad innovation and application prospects in the field of wound repair.

Abstract Image

受节肢动物启发的伤口愈合仿生材料的研究进展
节肢动物从组成到身体的特殊结构都蕴含着大量宝贵的仿生信息。尤其是其快速自愈能力和抗菌特性令人惊叹。节肢动物的仿生材料一直是伤口处理的有效方法。在此,我们确定了创建节肢动物生物仿生材料所需的四个主要维度,包括成分、行为、结构和内部反应。根据不同的维度,我们对已报道的节肢动物生物仿生材料进行了分类和介绍。抗菌、止血和促进愈合是人类开发的节肢动物活性成分的主要功能,其中大部分发挥了药物作用。我们认为,理想的节肢动物生物仿生材料应具有促进伤口愈合的作用,这需要通过结构和成分的优势来实现。表皮特殊的宏观和微观结构可为生物仿生材料提供良好的机械支撑。仿生材料的药物释放规律性可以参考节肢动物的攻击性和分泌行为。节肢动物体内的物质合成也值得注意,我们可以借鉴这些特殊反应来完成材料的快速制备。节肢动物启发的仿生材料在伤口修复领域具有广阔的创新和应用前景。
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来源期刊
CiteScore
8.30
自引率
4.90%
发文量
303
审稿时长
30 days
期刊介绍: Materials Today Bio is a multidisciplinary journal that specializes in the intersection between biology and materials science, chemistry, physics, engineering, and medicine. It covers various aspects such as the design and assembly of new structures, their interaction with biological systems, functionalization, bioimaging, therapies, and diagnostics in healthcare. The journal aims to showcase the most significant advancements and discoveries in this field. As part of the Materials Today family, Materials Today Bio provides rigorous peer review, quick decision-making, and high visibility for authors. It is indexed in Scopus, PubMed Central, Emerging Sources, Citation Index (ESCI), and Directory of Open Access Journals (DOAJ).
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