Current trends and research hotspots in the study of flavonoids for ulcerative colitis: A bibliometric study.

IF 1.1 4区 医学 Q4 GASTROENTEROLOGY & HEPATOLOGY
Dingqi Li, Kaixi Ding, Wei Jiang, Ming Lei, Chaofang Lei
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引用次数: 0

Abstract

Background and study aims: Flavonoids have been shown to exhibit significant potential in treating ulcerative colitis (UC), and their mechanism of action is receiving increasing attention. This study was devoted to the bibliometric analysis of articles and review articles in flavonoid therapy for UC research between 2011 and 2022 to show publication trends and research hotspots.

Material and methods: The literature search data for the bibliometric analysis were obtained from the Web of Science Core Collection by searching for the terms "Flavonoids" and "Ulcerative colitis or Idiopathic Proctocolitis or colitis gravis or Inflammatory Bowel Disease, Ulcerative Colitis Type." Three software programs, Bibliometrix, CiteSpace, and VOSviewer, were used to perform a bibliometric analysis of the retrieved literature data.

Results: There were 181 publications on flavonoids for UC during the 12 years, with an upward trend in annual publications and an annual growth rate of 27.11 %. China had the highest cumulative number of publications, and Kyung Hee University was the academic institution with the most publications in this research area. In recent years, intestinal flora, intestinal barrier, apoptosis, tight protein junctions, and TLR4/ NF-κB pathway have become hot spots for research on flavonoids for UC. Grape seed analogs have been extensively investigated for treating UC in the past three years.

Conclusion: The results of this bibliometric study demonstrate the current status and trends of research on flavonoids for the treatment of UC and provide relevant researchers with hot topics and the latest research directions.

黄酮类化合物治疗溃疡性结肠炎研究的当前趋势和研究热点:文献计量学研究。
背景和研究目的:黄酮类化合物在治疗溃疡性结肠炎(UC)方面具有巨大潜力,其作用机制正受到越来越多的关注。本研究专门对2011年至2022年间黄酮类化合物治疗溃疡性结肠炎研究方面的文章和综述文章进行文献计量分析,以显示其发表趋势和研究热点:用于文献计量分析的文献检索数据来自Web of Science Core Collection,检索词为 "类黄酮 "和 "溃疡性结肠炎或特发性直肠结肠炎或结肠炎或炎症性肠病,溃疡性结肠炎类型"。我们使用 Bibliometrix、CiteSpace 和 VOSviewer 这三个软件对检索到的文献数据进行了文献计量分析:结果:12年间共有181篇关于黄酮类药物治疗UC的文献发表,年发表量呈上升趋势,年增长率为27.11%。中国的累计论文数量最多,庆熙大学是在该研究领域发表论文最多的学术机构。近年来,肠道菌群、肠道屏障、细胞凋亡、紧密蛋白连接和 TLR4/ NF-κB 通路已成为类黄酮治疗 UC 的研究热点。在过去的三年中,葡萄籽类似物被广泛用于治疗UC:这项文献计量学研究的结果展示了黄酮类化合物治疗UC的研究现状和趋势,为相关研究人员提供了热点话题和最新研究方向。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Arab Journal of Gastroenterology
Arab Journal of Gastroenterology Medicine-Gastroenterology
CiteScore
2.70
自引率
0.00%
发文量
52
期刊介绍: Arab Journal of Gastroenterology (AJG) publishes different studies related to the digestive system. It aims to be the foremost scientific peer reviewed journal encompassing diverse studies related to the digestive system and its disorders, and serving the Pan-Arab and wider community working on gastrointestinal disorders.
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