Understanding the burden of weekly somatrogon injections compared with daily somatropin injections in children with growth hormone deficiency: a plain language summary of publication.

IF 3.9 3区 医学 Q2 ENDOCRINOLOGY & METABOLISM
Therapeutic Advances in Endocrinology and Metabolism Pub Date : 2024-11-02 eCollection Date: 2024-01-01 DOI:10.1177/20420188241274363
Aristides K Maniatis, Mauri Carakushansky, Sonya Galcheva, Gnanagurudasan Prakasam, Larry A Fox, Adriana Dankovcikova, Jane Loftus, Andrew A Palladino, Maria de Los Angeles Resa, Carrie Turich Taylor, Mehul T Dattani, Jan Lebl
{"title":"Understanding the burden of weekly somatrogon injections compared with daily somatropin injections in children with growth hormone deficiency: a plain language summary of publication.","authors":"Aristides K Maniatis, Mauri Carakushansky, Sonya Galcheva, Gnanagurudasan Prakasam, Larry A Fox, Adriana Dankovcikova, Jane Loftus, Andrew A Palladino, Maria de Los Angeles Resa, Carrie Turich Taylor, Mehul T Dattani, Jan Lebl","doi":"10.1177/20420188241274363","DOIUrl":null,"url":null,"abstract":"<p><p>• For children with growth <b>hormone</b> deficiency, once-weekly <b>somatrogon</b> injections were less of a burden than once-daily <b>somatropin</b> injections. • The safety of weekly <b>somatrogon</b> was similar to that of daily <b>somatropin</b>. • Compared with daily <b>somatropin</b> injections, children with growth <b>hormone</b> deficiency may be less likely to miss weekly <b>somatrogon</b> injections.  ○ This is because weekly <b>somatrogon</b> injections were less of a burden and were less likely to interfere with daily activities compared with daily <b>somatropin</b> injections. The purpose of this plain language summary is to help you to understand the findings from recent research. • <b>Somatrogon</b> is used to treat the condition under study that is discussed in this summary. Approval varies by country; please check with your local provider for more details. • The results of this study may differ from those of other studies. Health professionals should make treatment decisions based on all available evidence and not on the results of a single study. <b>This original scientific article on which this summary is based was published in the <i>Journal of the Endocrine Society</i> and can be accessed for free at: https://academic.oup.com/jes/article/6/10/bvac117/6695276. The details of the original article are as follows:</b> <i>Aristides K. Maniatis, Mauri Carakushansky, Sonya Galcheva, Gnanagurudasan Prakasam, Larry A. Fox, Adriana Dankovcikova, Jane Loftus, Andrew A. Palladino, Maria de los Angeles Resa, Carrie Turich Taylor, Mehul T. Dattani, Jan Lebl</i>. Treatment burden of weekly <b>somatrogon</b> versus daily <b>somatropin</b> in children with growth <b>hormone</b> deficiency: a randomized study. <i>J Endocr Soc</i> 2022; 6(10): bvac117. DOI: 10.1210/jendso/bvac117.</p>","PeriodicalId":22998,"journal":{"name":"Therapeutic Advances in Endocrinology and Metabolism","volume":null,"pages":null},"PeriodicalIF":3.9000,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531668/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Therapeutic Advances in Endocrinology and Metabolism","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/20420188241274363","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
引用次数: 0

Abstract

• For children with growth hormone deficiency, once-weekly somatrogon injections were less of a burden than once-daily somatropin injections. • The safety of weekly somatrogon was similar to that of daily somatropin. • Compared with daily somatropin injections, children with growth hormone deficiency may be less likely to miss weekly somatrogon injections.  ○ This is because weekly somatrogon injections were less of a burden and were less likely to interfere with daily activities compared with daily somatropin injections. The purpose of this plain language summary is to help you to understand the findings from recent research. • Somatrogon is used to treat the condition under study that is discussed in this summary. Approval varies by country; please check with your local provider for more details. • The results of this study may differ from those of other studies. Health professionals should make treatment decisions based on all available evidence and not on the results of a single study. This original scientific article on which this summary is based was published in the Journal of the Endocrine Society and can be accessed for free at: https://academic.oup.com/jes/article/6/10/bvac117/6695276. The details of the original article are as follows: Aristides K. Maniatis, Mauri Carakushansky, Sonya Galcheva, Gnanagurudasan Prakasam, Larry A. Fox, Adriana Dankovcikova, Jane Loftus, Andrew A. Palladino, Maria de los Angeles Resa, Carrie Turich Taylor, Mehul T. Dattani, Jan Lebl. Treatment burden of weekly somatrogon versus daily somatropin in children with growth hormone deficiency: a randomized study. J Endocr Soc 2022; 6(10): bvac117. DOI: 10.1210/jendso/bvac117.

了解生长激素缺乏症儿童每周注射索马曲贡与每天注射索马托品的负担比较:通俗易懂的出版物摘要。
- 对于生长激素缺乏症儿童来说,每周注射一次索马曲贡比每天注射一次索马托品造成的负担要小。- 每周注射一次索马曲贡的安全性与每天注射一次索马托品的安全性相似。- 与每天注射一次索马特罗普相比,生长激素缺乏症患儿错过每周一次索马特罗普注射的可能性较小。这是因为与每天注射索马托品相比,每周注射一次索马托品的负担较轻,而且不太可能影响日常活动。这份通俗易懂的摘要旨在帮助您了解最新的研究结果。- Somatrogon用于治疗本摘要中讨论的研究中的病症。批准情况因国家而异,详情请咨询当地医疗机构。- 本研究结果可能与其他研究结果不同。医疗专业人员应根据所有可用证据而非单项研究结果做出治疗决定。本摘要所依据的原始科学文章发表在《内分泌学会杂志》(Journal of the Endocrine Society)上,可在以下网址免费获取:https://academic.oup.com/jes/article/6/10/bvac117/6695276。原文详情如下:Aristides K. Maniatis, Mauri Carakushansky, Sonya Galcheva, Gnanagurudasan Prakasam, Larry A. Fox, Adriana Dankovcikova, Jane Loftus, Andrew A. Palladino, Maria de los Angeles Resa, Carrie Turich Taylor, Mehul T. Dattani, Jan Lebl.生长激素缺乏症儿童每周使用索马特罗贡与每天使用索马特罗宾的治疗负担:一项随机研究。J Endocr Soc 2022; 6(10): bvac117.DOI: 10.1210/jendso/bvac117.
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Therapeutic Advances in Endocrinology and Metabolism
Therapeutic Advances in Endocrinology and Metabolism Medicine-Endocrinology, Diabetes and Metabolism
CiteScore
7.70
自引率
2.60%
发文量
42
审稿时长
8 weeks
期刊介绍: Therapeutic Advances in Endocrinology and Metabolism delivers the highest quality peer-reviewed articles, reviews, and scholarly comment on pioneering efforts and innovative studies across all areas of endocrinology and metabolism.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信