Fibromyalgia and sexual dysfunction in women: A systematic review and meta-analysis

IF 2.1 4区医学 Q2 OBSTETRICS & GYNECOLOGY

European journal of obstetrics, gynecology, and reproductive biology Pub Date : 2024-10-29 DOI:10.1016/j.ejogrb.2024.10.050

Indiamara Deggerone , Maria Laura Rodrigues Uggioni , Peterson Rech , Vitória Silveira , Tamy Colonetti , Luciane Bisognin Ceretta , Maria Inês Rosa , Antônio José Grande

{"title":"Fibromyalgia and sexual dysfunction in women: A systematic review and meta-analysis","authors":"Indiamara Deggerone , Maria Laura Rodrigues Uggioni , Peterson Rech , Vitória Silveira , Tamy Colonetti , Luciane Bisognin Ceretta , Maria Inês Rosa , Antônio José Grande","doi":"10.1016/j.ejogrb.2024.10.050","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><div>Fibromyalgia syndrome (FMS) is a chronic condition that associates pain, sleep disturbances, and cognitive changes. Recent evidence shows that sexual dysfunction is also associated with fibromyalgia, further affecting patients’ quality of life.</div></div><div><h3>Objective</h3><div>Our aim was to explore the association between FMS and sexual dysfunction (SD) in women.</div></div><div><h3>Methods</h3><div>A comprehensive search strategy was carried out, using the keywords “fibromyalgia” and “sexual dysfunction” and their synonyms. The databases used were MEDLINE, EMBASE, Scopus, Biomed Central, Web of Science, CINAHL, IBECS, LILACS, Congress Abstracts, and gray literature sources like Google Scholar. Studies published from January 1990 to August 2023 were considered, without imposing any language restrictions. The inclusion criteria involved studies that investigated individuals diagnosed with FMS and who suffered from sexual dysfunction, while studies that did not meet these criteria were excluded. The methodological quality of the included studies was assessed using the New Castle Ottawa tool. The results were presented in tables and forest graphs generated by the RevMan 5.4 software.</div></div><div><h3>Results</h3><div>27 studies were included, 10 of which were case-control and 17 were cross-sectional. These studies were published between 2005 and 2023, with participants aged between 18 and 81 years. Patients with FMS performed markedly worse than healthy controls in all domains of sexual dysfunction assessed. The methodological quality of the included studies was classified as moderate to high.</div></div><div><h3>Conclusion</h3><div>Compared to healthy women, the findings indicate a negative correlation between sexual dysfunction and fibromyalgia. These results underscore the significance of addressing sexual disturbances as a source of distress in the context of fibromyalgia syndrome. It becomes evident that incorporating psychological therapies that encompass emotional, physical, and sexual health could be a pivotal component in the comprehensive treatment of fibromyalgia syndrome.</div></div>","PeriodicalId":11975,"journal":{"name":"European journal of obstetrics, gynecology, and reproductive biology","volume":"303 ","pages":"Pages 171-179"},"PeriodicalIF":2.1000,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European journal of obstetrics, gynecology, and reproductive biology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0301211524005979","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Introduction

Fibromyalgia syndrome (FMS) is a chronic condition that associates pain, sleep disturbances, and cognitive changes. Recent evidence shows that sexual dysfunction is also associated with fibromyalgia, further affecting patients’ quality of life.

Objective

Our aim was to explore the association between FMS and sexual dysfunction (SD) in women.

Methods

A comprehensive search strategy was carried out, using the keywords “fibromyalgia” and “sexual dysfunction” and their synonyms. The databases used were MEDLINE, EMBASE, Scopus, Biomed Central, Web of Science, CINAHL, IBECS, LILACS, Congress Abstracts, and gray literature sources like Google Scholar. Studies published from January 1990 to August 2023 were considered, without imposing any language restrictions. The inclusion criteria involved studies that investigated individuals diagnosed with FMS and who suffered from sexual dysfunction, while studies that did not meet these criteria were excluded. The methodological quality of the included studies was assessed using the New Castle Ottawa tool. The results were presented in tables and forest graphs generated by the RevMan 5.4 software.

Results

27 studies were included, 10 of which were case-control and 17 were cross-sectional. These studies were published between 2005 and 2023, with participants aged between 18 and 81 years. Patients with FMS performed markedly worse than healthy controls in all domains of sexual dysfunction assessed. The methodological quality of the included studies was classified as moderate to high.

Conclusion

Compared to healthy women, the findings indicate a negative correlation between sexual dysfunction and fibromyalgia. These results underscore the significance of addressing sexual disturbances as a source of distress in the context of fibromyalgia syndrome. It becomes evident that incorporating psychological therapies that encompass emotional, physical, and sexual health could be a pivotal component in the comprehensive treatment of fibromyalgia syndrome.

查看原文本刊更多论文

纤维肌痛与女性性功能障碍：系统回顾和荟萃分析。

引言纤维肌痛综合征（FMS）是一种慢性疾病，与疼痛、睡眠障碍和认知改变有关。最近的证据显示，性功能障碍也与纤维肌痛有关，进一步影响了患者的生活质量：我们的目的是探讨纤维肌痛与女性性功能障碍（SD）之间的关联：使用关键词 "纤维肌痛 "和 "性功能障碍 "及其同义词进行了全面搜索。使用的数据库包括 MEDLINE、EMBASE、Scopus、Biomed Central、Web of Science、CINAHL、IBECS、LILACS、Congress Abstracts 以及 Google Scholar 等灰色文献来源。考虑的研究发表于 1990 年 1 月至 2023 年 8 月，没有任何语言限制。纳入标准包括对诊断为 FMS 并患有性功能障碍的患者进行调查的研究，而不符合这些标准的研究则被排除在外。纳入研究的方法学质量采用新堡渥太华工具进行评估。结果：共纳入 27 项研究，其中 10 项为病例对照研究，17 项为横断面研究。这些研究发表于2005年至2023年之间，参与者的年龄在18岁至81岁之间。与健康对照组相比，FMS 患者在性功能障碍的所有评估领域中的表现都明显较差。所纳入研究的方法学质量分为中度到高度：结论：与健康女性相比，研究结果表明性功能障碍与纤维肌痛之间存在负相关。这些结果表明，在纤维肌痛综合征的情况下，将性功能障碍作为一种困扰源加以解决具有重要意义。显而易见，在纤维肌痛综合症的综合治疗中，包含情感、身体和性健康在内的心理疗法可能是一个关键组成部分。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

European journal of obstetrics, gynecology, and reproductive biology 医学-妇产科学

CiteScore

4.60

自引率

3.80%

发文量

898

审稿时长

8.3 weeks

期刊介绍： The European Journal of Obstetrics & Gynecology and Reproductive Biology is the leading general clinical journal covering the continent. It publishes peer reviewed original research articles, as well as a wide range of news, book reviews, biographical, historical and educational articles and a lively correspondence section. Fields covered include obstetrics, prenatal diagnosis, maternal-fetal medicine, perinatology, general gynecology, gynecologic oncology, uro-gynecology, reproductive medicine, infertility, reproductive endocrinology, sexual medicine and reproductive ethics. The European Journal of Obstetrics & Gynecology and Reproductive Biology provides a forum for scientific and clinical professional communication in obstetrics and gynecology throughout Europe and the world.