Assessment of chronical total occlusions management in France: The ENCOCHE Registry, a prospective, multicentric study.

IF 2.3 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
Luc Cornillet, Thierry Lefèvre, Julien Lemoine, Andrea Zuffi, Alexandre Avran, Richard Gervasoni, Eugenio La Scala, Emmanuel Teiger, Matthieu Godin, Patrick Staat, Lionel Mangin, Raphaël Philippart, Katrien Blanchart, Thomas Hovasse, Philippe Brunel, Erwann Bressollette, Vincent Letocart, Vincent Bataille, Nicolas Boudou
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引用次数: 0

Abstract

Background: Coronary chronic total occlusions (CTO) are frequent, and coronary angioplasty has been increasingly used in recent years for lesion revascularisation. However, to date, no dedicated multicentric prospective study is available in France.

Aim: To describe the characteristics of CTO patients and to assess current treatment strategies in French catheterisation laboratory practice.

Methods: Patients presenting with CTOs were included from 16/09/2021 to 13/12/2021 over two consecutive prospective phases. In phase I (one month), data were collected to include all patients presenting CTO at diagnostic angiography. In phase II (two months), data were collected focusing on patients who underwent CTO-PCI.

Results: A total of 1303 patients (1460 CTOs) were included in 68 French centres. The mean age was 67.7±10.7 years and 84.3% of the patients were men. The prevalence of prior PCI (44.6%), and diabetes mellitus (35.6%) was high. In phase I, multivessel coronary artery disease was detected in two-thirds of cases, and most of them (88.5%) had a single CTO. The mean J-CTO score was 1.9±1.2, with a proportion of difficult and very difficult CTO (J CTO score ≥2) of 61.1%. The selected treatment was medical therapy in 57% of cases, coronary angioplasty in 30% and bypass surgery in 13%. In phase II, 528 patients were included with a mean J-CTO score of 1.8±1.2. Successful guidewire crossing through CTO lesion was obtained with an antegrade access in 89% of patients. Procedural success rate of CTO-PCI was 80%, with a rate of major in-hospital complications of 1% (death: 0.4%, MI: 0.2%, stroke: 0.2%, emergency CABG: 0.2%).

Conclusion: This prospective study provides a snapshot of CTOs prevalence and CTO treatment strategies in France in 2021.

法国慢性全动脉闭塞症管理评估:ENCOCHE登记处是一项前瞻性多中心研究。
背景:冠状动脉慢性全闭塞(CTO)是一种常见病,近年来冠状动脉血管成形术越来越多地被用于病变血管再通。目的:描述 CTO 患者的特征,评估法国导管室实践中的现行治疗策略:方法:在 2021 年 9 月 16 日至 2021 年 12 月 13 日的两个连续的前瞻性阶段中,纳入了 CTO 患者。第一阶段(一个月)收集的数据包括所有在诊断性血管造影中发现 CTO 的患者。第二阶段(两个月)收集的数据主要针对接受CTO-PCI的患者:结果:法国68个中心共纳入1303名患者(1460例CTO)。平均年龄为(67.7±10.7)岁,84.3%的患者为男性。既往PCI(44.6%)和糖尿病(35.6%)患病率较高。在第一阶段,三分之二的病例发现了多支冠状动脉疾病,其中大部分(88.5%)为单支CTO。平均J-CTO评分为1.9±1.2,困难和非常困难CTO(J CTO评分≥2)的比例为61.1%。57%的病例选择药物治疗,30%选择冠状动脉血管成形术,13%选择搭桥手术。第二阶段共纳入 528 例患者,平均 J-CTO 评分为 1.8±1.2。89%的患者通过前行入路成功导丝穿过CTO病变。CTO-PCI手术成功率为80%,主要院内并发症发生率为1%(死亡:0.4%,心肌梗死:0.2%,中风:0.2%,急诊CABG:0.2%):这项前瞻性研究为 2021 年法国的 CTO 发病率和 CTO 治疗策略提供了一个缩影。
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来源期刊
Archives of Cardiovascular Diseases
Archives of Cardiovascular Diseases 医学-心血管系统
CiteScore
4.40
自引率
6.70%
发文量
87
审稿时长
34 days
期刊介绍: The Journal publishes original peer-reviewed clinical and research articles, epidemiological studies, new methodological clinical approaches, review articles and editorials. Topics covered include coronary artery and valve diseases, interventional and pediatric cardiology, cardiovascular surgery, cardiomyopathy and heart failure, arrhythmias and stimulation, cardiovascular imaging, vascular medicine and hypertension, epidemiology and risk factors, and large multicenter studies. Archives of Cardiovascular Diseases also publishes abstracts of papers presented at the annual sessions of the Journées Européennes de la Société Française de Cardiologie and the guidelines edited by the French Society of Cardiology.
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