Surgical Treatment of Atrial Septal Defects.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2024-09-29 eCollection Date: 2024-10-01 DOI:10.31083/j.rcm2510350
Philippe Grieshaber, Christoph Jaschinski, Mina Farag, Elizabeth Fonseca-Escalante, Matthias Gorenflo, Matthias Karck, Tsvetomir Loukanov
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引用次数: 0

Abstract

Atrial septal defects (ASDs) are among the most prevalent congenital cardiac malformations. Closure of the defect and repair of associated cardiac malformations are typically indicated if an ASD is hemodynamically significant or symptomatic. This narrative review aims to summarize key aspects of surgical ASD closures. A non-systematic literature review was conducted to cover surgically relevant aspects of (developmental) anatomy, morphology, and treatment. ASDs result from diverse developmental alterations, leading to subtype-specific associated cardiac malformations, meaning surgical therapy varies accordingly. Presently, surgical repair yields excellent outcomes for all ASD subtypes, with minimally invasive approaches, especially in adults, increasingly employed for ASD closure. Surgical ASD repair is safe with excellent results. However, familiarity with ASD subtypes and typically associated lesions is crucial for optimal patient management.

心房间隔缺损的手术治疗。
房间隔缺损(ASD)是最常见的先天性心脏畸形之一。如果 ASD 在血流动力学上有显著影响或有症状,通常需要进行缺损闭合和相关心脏畸形的修复。这篇叙述性综述旨在总结 ASD 闭合手术的主要方面。我们进行了非系统性的文献综述,涵盖了(发育)解剖学、形态学和治疗的手术相关方面。ASD 由不同的发育改变引起,导致亚型特异性的相关心脏畸形,这意味着手术治疗也相应不同。目前,手术修复对所有 ASD 亚型都有很好的疗效,微创方法也越来越多地用于 ASD 闭合,尤其是成人。手术修复 ASD 非常安全,效果极佳。然而,熟悉 ASD 亚型和典型的相关病变对于优化患者管理至关重要。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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