Improvement of the Immunity System Through Sports: Novel Regulatory Mechanisms for Hypertension.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-10-25 eCollection Date: 2024-10-01 DOI:10.31083/j.rcm2510385

Jin Yang, Rui Sun, Zuowei Pei

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引用次数: 0

Abstract

Hypertension and its resulting target organ damage is a complex process associated with a range of physiological and molecular factors, including immune regulation. The profound effects of exercise on normal immune system function and the development and progression of hypertension are well known. This review aims to create new avenues for preventing and treating hypertension and its associated target organ damage. This narrative review emphasizes the role of exercise training in the prevention/treatment of hypertension development through immune response modulation and presents current perspectives on the available scientific evidence. Several studies have shown that exercise regulates hypertension by altering immune cells, which is partly attributable to the anti-inflammatory effects of exercise training. Regular exercise modifies immune modulation and could represent a new mechanism for regulating hypertension. Although the utilization of exercise training and the immune system in conjunction for treating and preventing hypertension is still in its early stages, current scientific literature indicates numerous potential physiological links between exercise training, the immune system, and hypertension.

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通过运动改善免疫系统：高血压的新型调节机制。

高血压及其导致的靶器官损伤是一个复杂的过程，与一系列生理和分子因素（包括免疫调节）有关。众所周知，运动对正常免疫系统功能以及高血压的发生和发展有着深远的影响。本综述旨在为预防和治疗高血压及其相关靶器官损伤开辟新途径。这篇叙述性综述强调了运动训练通过调节免疫反应在预防/治疗高血压发展中的作用，并介绍了现有科学证据的最新观点。多项研究表明，运动通过改变免疫细胞来调节高血压，这部分归因于运动训练的抗炎作用。经常运动可改变免疫调节，可能是调节高血压的一种新机制。尽管将运动训练和免疫系统结合起来用于治疗和预防高血压仍处于早期阶段，但目前的科学文献表明，运动训练、免疫系统和高血压之间存在许多潜在的生理联系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.