Advancement in Multi-omics approaches for Uterine Sarcoma.

IF 9.5 2区 医学 Q1 MEDICINE, RESEARCH & EXPERIMENTAL
Wuyang Wang, Yu Hu, Fangfang Fu, Wu Ren, Tian Wang, Shixuan Wang, Yan Li
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引用次数: 0

Abstract

Uterine sarcoma (US) is a rare malignant tumor that has various pathological types and high heterogeneity in the female reproductive system. Its subtle early symptoms, frequent recurrence, and resistance to radiation and chemotherapy make the prognosis for US patients very poor. Therefore, understanding the molecular mechanisms underlying tumorigenesis and progression is essential for an accurate diagnosis and targeted therapy to improve patient outcomes. Recent advancements in high-throughput molecular sequencing have allowed for a deeper understanding of diseases through multi-omics technologies. In this review, the latest progress and future potential of multi-omics technologies in US research is examined, and their roles in biomarker discovery and their application in the precise diagnosis and treatment of US are highlighted.

子宫肉瘤多组学方法的进展。
子宫肉瘤(US)是一种罕见的恶性肿瘤,在女性生殖系统中具有多种病理类型和高度异质性。其早期症状不明显,复发率高,对放疗和化疗耐药,使得子宫肉瘤患者的预后非常差。因此,了解肿瘤发生和发展的分子机制对于准确诊断和靶向治疗以改善患者预后至关重要。高通量分子测序技术的最新进展使得人们可以通过多组学技术更深入地了解疾病。在这篇综述中,我们探讨了多组学技术在美国研究中的最新进展和未来潜力,并重点介绍了它们在生物标志物发现中的作用及其在美国精确诊断和治疗中的应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biomarker Research
Biomarker Research Biochemistry, Genetics and Molecular Biology-Molecular Medicine
CiteScore
15.80
自引率
1.80%
发文量
80
审稿时长
10 weeks
期刊介绍: Biomarker Research, an open-access, peer-reviewed journal, covers all aspects of biomarker investigation. It seeks to publish original discoveries, novel concepts, commentaries, and reviews across various biomedical disciplines. The field of biomarker research has progressed significantly with the rise of personalized medicine and individual health. Biomarkers play a crucial role in drug discovery and development, as well as in disease diagnosis, treatment, prognosis, and prevention, particularly in the genome era.
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