Umbilical cord blood gentamicin concentrations following maternally-administered intrapartum exposures.

IF 3.1 3区医学 Q1 PEDIATRICS

Pediatric Research Pub Date : 2024-10-30 DOI:10.1038/s41390-024-03698-z

Sarah A Coggins, Kelly C Wade, Kevin M Watt, Kevin J Downes, Karen M Puopolo

引用次数: 0

Abstract

Impact: We identified cord blood gentamicin concentrations that were higher than anticipated, and above clinical targets for immediate gentamicin re-dosing after birth. Incorporation of gentamicin levels at birth may aid in optimizing postnatal gentamicin dosing among infants exposed to intrapartum gentamicin.

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产前母体注射庆大霉素后脐带血中庆大霉素的浓度。

影响：我们发现脐带血中庆大霉素的浓度高于预期，也高于产后立即重新使用庆大霉素的临床目标值。结合出生时的庆大霉素水平，有助于优化产后庆大霉素用药。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pediatric Research 医学-小儿科

CiteScore

6.80

自引率

5.60%

发文量

473

审稿时长

3-8 weeks

期刊介绍： Pediatric Research publishes original papers, invited reviews, and commentaries on the etiologies of children''s diseases and disorders of development, extending from molecular biology to epidemiology. Use of model organisms and in vitro techniques relevant to developmental biology and medicine are acceptable, as are translational human studies