A Case of Syphilis With Ocular Involvement: Persistent Negative Serology in a Patient With Multiple Sclerosis.

IF 3.8 4区医学 Q2 IMMUNOLOGY

Open Forum Infectious Diseases Pub Date : 2024-10-29 eCollection Date: 2024-10-01 DOI:10.1093/ofid/ofae563

Luca Pipitò, Irene Ganci, Andrea Cicero, Alice Annalisa Medaglia, Simona D'Avenia, Edoardo Mandalà, Cinzia Calà, Paola Di Carlo, Antonio Cascio

引用次数: 0

Abstract

Diagnostic algorithms for syphilis are based on serology. However, with the advent of immunosuppressive therapies, these algorithms may fail. We report a case of an individual with multiple sclerosis on treatment with ofatumumab and secondary syphilis with visual and auditory systems involvement and persistent negative treponemal and nontreponemal tests.

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一例眼部受累的梅毒患者：多发性硬化症患者血清持续阴性。

梅毒的诊断算法以血清学为基础。然而，随着免疫抑制疗法的出现，这些算法可能会失效。我们报告了一例多发性硬化症患者的病例，患者在接受ofatumumab治疗后出现继发性梅毒，视觉和听觉系统受累，特雷波及非特雷波及梅毒试验持续阴性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Open Forum Infectious Diseases Medicine-Neurology (clinical)

CiteScore

6.70

自引率

4.80%

发文量

630

审稿时长

9 weeks

期刊介绍： Open Forum Infectious Diseases provides a global forum for the publication of clinical, translational, and basic research findings in a fully open access, online journal environment. The journal reflects the broad diversity of the field of infectious diseases, and focuses on the intersection of biomedical science and clinical practice, with a particular emphasis on knowledge that holds the potential to improve patient care in populations around the world. Fully peer-reviewed, OFID supports the international community of infectious diseases experts by providing a venue for articles that further the understanding of all aspects of infectious diseases.