Association Between Adverse Childhood Experiences and Cognitive Decline: Findings From the Behavioral Risk Factor Surveillance System, 2015-2016.

IF 1.6 4区医学 Q3 CLINICAL NEUROLOGY

Journal of Nervous and Mental Disease Pub Date : 2024-11-01 DOI:10.1097/NMD.0000000000001790

Gaurav Chaudhari, Darshini Vora, Chintan Trivedi, Preetam Reddy, Krishna Priya Bodicherla, Mahwish Adnan, Ramu Vadukapuram, Priya Durga Kodi, Kaushal Shah, Sruti Patel, Zeeshan Mansuri, Shailesh Jain

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Abstract

Abstract: We aim to study Adverse childhood experiences' (ACEs') association with cognitive decline during adulthood. We reviewed data on subjective cognitive decline (SCD) for those ≥45 years of age. Logistic regression analysis, odds ratio, and 95% confidence interval (CI) assessed the association between ACEs and SCD. We analyzed an adult survey (N = 3900, mean age: 60.9 years, male: 46%). The most common ACE reported was household substance abuse (22.4%), followed by parental divorce/separation (20.9%). The prevalence of SCD in those having at least one ACE was higher than those without any (16.5% vs. 8.1%, p < 0.001). SCD positively correlated with the number of ACEs (p < 0.001). The odds of SCD increase in proportion to the increase in the number of ACEs experienced. These findings should be replicated in a larger population while controlling for confounding factors.

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童年不良经历与认知能力下降之间的关系：2015-2016年行为风险因素监测系统的研究结果》（Finding from the Behavioral Risk Factor Surveillance System, 2015-2016）。

摘要：我们旨在研究童年不良经历（ACE）与成年后认知能力下降之间的关系。我们回顾了年龄≥45 岁人群的主观认知能力下降（SCD）数据。逻辑回归分析、几率比和 95% 置信区间 (CI) 评估了 ACE 与 SCD 之间的关系。我们分析了一项成人调查（N = 3900，平均年龄：60.9 岁，男性：46%）。最常见的 ACE 是家庭药物滥用（22.4%），其次是父母离婚/分居（20.9%）。在至少有一项 ACE 的人群中，SCD 患病率高于没有任何 ACE 的人群（16.5% 对 8.1%，P < 0.001）。SCD 与 ACE 的数量呈正相关（p < 0.001）。发生 SCD 的几率与经历的 ACE 数量的增加成正比。这些研究结果应在更大的人群中进行复制，同时控制混杂因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Nervous and Mental Disease 医学-精神病学

CiteScore

2.90

自引率

5.30%

发文量

233

审稿时长

3-8 weeks

期刊介绍： The Journal of Nervous and Mental Disease publishes peer-reviewed articles containing new data or ways of reorganizing established knowledge relevant to understanding and modifying human behavior, especially that defined as impaired or diseased, and the context, applications and effects of that knowledge. Our policy is summarized by the slogan, "Behavioral science for clinical practice." We consider articles that include at least one behavioral variable, clear definition of study populations, and replicable research designs. Authors should use the active voice and first person whenever possible.