Yang Jiao, Haimang Wang, Xiechuan Weng, Jihang Wang, Ying Li, Jian Shen, Weiwei Zhao, Qing Xi, Hongyu Zhang, Zhenhong Fu
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引用次数: 0
Abstract
In this study, supramolecular self-assembled nanoparticles were developed with multi-functional properties of macrophage escape, cardiac targeting, and drug release for the treatment of myocardial infarction. The nanoparticles reduced cardiomyocyte apoptosis, alleviated myocardial interstitial fibrosis, and enhanced cardiac function based on the mechanism of the enhancement in mitophagy and alleviation in mitochondrial damage (e563).
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