Chemomobilisation Using Gemcitabine-Oxaliplatin for Salvage High Dose Chemotherapy and Autologous Stem Cell Transplant in Advanced Testicular Germ Cell Cancer

IF 2.3 3区医学 Q3 ONCOLOGY

Clinical genitourinary cancer Pub Date : 2024-10-04 DOI:10.1016/j.clgc.2024.102234

Jane McKenzie , Ciara Conduit , Melissa Ng Liet Hing , Kristina Zlatic , Kerrie Stokes , Sharlea Disney , Amit Khot , Simon J. Harrison , Jeremy Lewin , Ben Tran

引用次数: 0

Abstract

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At relapse, testicular germ cell tumors may be treated with high-dose chemotherapy and autologous stem cell transplant.
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Traditional chemomobilisation protocols for autologous stem cell transplant may be unsuitable for pretreated patients.
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Gemcitabine and Oxaliplatin provides satisfactory stem cell mobilization and treatment outcomes for this high-risk group.

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在晚期睾丸生殖细胞癌中使用吉西他滨-奥沙利铂化疗动员疗法进行挽救性大剂量化疗和自体干细胞移植

-睾丸生殖细胞肿瘤复发时，可采用大剂量化疗和自体干细胞移植治疗。-自体干细胞移植的传统化学动员方案可能不适合预处理患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical genitourinary cancer 医学-泌尿学与肾脏学

CiteScore

5.20

自引率

6.20%

发文量

201

审稿时长

54 days

期刊介绍： Clinical Genitourinary Cancer is a peer-reviewed journal that publishes original articles describing various aspects of clinical and translational research in genitourinary cancers. Clinical Genitourinary Cancer is devoted to articles on detection, diagnosis, prevention, and treatment of genitourinary cancers. The main emphasis is on recent scientific developments in all areas related to genitourinary malignancies. Specific areas of interest include clinical research and mechanistic approaches; drug sensitivity and resistance; gene and antisense therapy; pathology, markers, and prognostic indicators; chemoprevention strategies; multimodality therapy; and integration of various approaches.