42 (PB030): A novel small-molecule CBP/p300 HAT domain inhibitor demonstrates potent in vivo activity and a favorable safety profile in preclinical species

IF 7.6 1区医学 Q1 ONCOLOGY

European Journal of Cancer Pub Date : 2024-10-01 DOI:10.1016/j.ejca.2024.114570

K. Hearn, M. Ahn, L. Bevan, G. Chessari, M. Clark, B. Cons, J. Espana-agusti, K. Ferro, A. Howard, J. Lyons, V. Martins, C. Morgillo, N. Palmer, M. Rapti, A. Shah, T. Smyth, M. Unbekandt, D. Varshney, C. Hamlett

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42 (PB030)：一种新型小分子 CBP/p300 HAT 结构域抑制剂在临床前物种中显示出强大的体内活性和良好的安全性特征

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来源期刊

European Journal of Cancer 医学-肿瘤学

CiteScore

11.50

自引率

4.80%

发文量

953

审稿时长

23 days

期刊介绍： The European Journal of Cancer (EJC) serves as a comprehensive platform integrating preclinical, digital, translational, and clinical research across the spectrum of cancer. From epidemiology, carcinogenesis, and biology to groundbreaking innovations in cancer treatment and patient care, the journal covers a wide array of topics. We publish original research, reviews, previews, editorial comments, and correspondence, fostering dialogue and advancement in the fight against cancer. Join us in our mission to drive progress and improve outcomes in cancer research and patient care.