Thermal modeling and its role in management of bifurcation aneurysms and associated ischemic complications in the middle cerebral artery

IF 5.1 3区工程技术 Q2 ENERGY & FUELS

Thermal Science and Engineering Progress Pub Date : 2024-10-01 DOI:10.1016/j.tsep.2024.102985

Tengyun Guo , Xiaoshu Wang , Shixin Peng, Yulong Qiu, Ji Zhu, Xiaodong Zhang, Rui Xu

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引用次数: 0

Abstract

Bifurcated aneurysm of cerebral artery is a common cerebrovascular disease, which can easily lead to serious ischemic complications. Traditional treatments face challenges of risk and effectiveness. Therefore, it is particularly important to explore new therapeutic strategies. In recent years, the application of thermal modeling techniques in medical biological systems has provided a new perspective for the analysis of hemodynamics and tissue thermal response. The purpose of this study was to investigate the role of heat model in the treatment of bifurcated cerebral artery aneurysms and their associated ischemic complications, and to evaluate its potential value in understanding disease mechanisms and optimizing treatment protocols. In this study, a three-dimensional thermal model was used to simulate the heat conduction and blood flow characteristics of the bifurcated parts of cerebral arteries. Combined with the clinical data of patients, the influence of the thermal model on the formation mechanism of aneurysms and the prognosis evaluation of ischemic complications were analyzed through numerical calculation and experimental verification. Compare the performance of different treatment methods in thermal models. The thermal model shows that the temperature distribution at the aneurysm site is closely related to the blood flow velocity, and the local temperature increase may promote thrombosis and lead to ischemic complications. The treatment regimen optimized by the thermal model showed significant improvement in the simulation, reducing the risk of complications and improving hemodynamic parameters. Heat model can reveal the dynamic relationship between blood flow and temperature in the study of cerebral artery bifurcation aneurysm, and provide theoretical support for clinical treatment.

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热建模及其在治疗大脑中动脉分叉动脉瘤和相关缺血性并发症中的作用

脑动脉分叉动脉瘤是一种常见的脑血管疾病，极易引发严重的缺血性并发症。传统的治疗方法面临着风险和有效性的挑战。因此，探索新的治疗策略显得尤为重要。近年来，热建模技术在医学生物系统中的应用为分析血液动力学和组织热反应提供了新的视角。本研究旨在探讨热模型在治疗大脑分叉动脉瘤及其相关缺血性并发症中的作用，并评估其在了解疾病机制和优化治疗方案方面的潜在价值。本研究采用三维热模型模拟脑动脉分叉部位的热传导和血流特征。结合患者的临床数据，通过数值计算和实验验证，分析了热模型对动脉瘤形成机制和缺血并发症预后评估的影响。比较不同治疗方法在热模型中的表现。热模型显示动脉瘤部位的温度分布与血流速度密切相关，局部温度升高可能促进血栓形成，导致缺血并发症。通过热模型优化的治疗方案在模拟中显示出明显的改善，降低了并发症的风险，改善了血液动力学参数。热模型可以揭示脑动脉分叉动脉瘤研究中血流与温度的动态关系，为临床治疗提供理论支持。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Thermal Science and Engineering Progress Chemical Engineering-Fluid Flow and Transfer Processes

CiteScore

7.20

自引率

10.40%

发文量

327

审稿时长

41 days

期刊介绍： Thermal Science and Engineering Progress (TSEP) publishes original, high-quality research articles that span activities ranging from fundamental scientific research and discussion of the more controversial thermodynamic theories, to developments in thermal engineering that are in many instances examples of the way scientists and engineers are addressing the challenges facing a growing population – smart cities and global warming – maximising thermodynamic efficiencies and minimising all heat losses. It is intended that these will be of current relevance and interest to industry, academia and other practitioners. It is evident that many specialised journals in thermal and, to some extent, in fluid disciplines tend to focus on topics that can be classified as fundamental in nature, or are ‘applied’ and near-market. Thermal Science and Engineering Progress will bridge the gap between these two areas, allowing authors to make an easy choice, should they or a journal editor feel that their papers are ‘out of scope’ when considering other journals. The range of topics covered by Thermal Science and Engineering Progress addresses the rapid rate of development being made in thermal transfer processes as they affect traditional fields, and important growth in the topical research areas of aerospace, thermal biological and medical systems, electronics and nano-technologies, renewable energy systems, food production (including agriculture), and the need to minimise man-made thermal impacts on climate change. Review articles on appropriate topics for TSEP are encouraged, although until TSEP is fully established, these will be limited in number. Before submitting such articles, please contact one of the Editors, or a member of the Editorial Advisory Board with an outline of your proposal and your expertise in the area of your review.