The international expert consensus on management of external auditory canal carcinoma.

IF 1.9 3区医学 Q2 OTORHINOLARYNGOLOGY

European Archives of Oto-Rhino-Laryngology Pub Date : 2024-10-28 DOI:10.1007/s00405-024-09033-w

Pei Zhou, Rubens de Brito, Yong Cui, Simon Lloyd, Henricus Kunst, J Walter Kutz, Navin Mani, In Seok Moon, Badr Eldin Mostafa, Cindy Nabuurs, Sampath Chandra Prasad Rao, Bingbin Xie, Yibo Zhang, Chunfu Dai

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引用次数: 0

Abstract

Purpose: The objective of this consensus is to provide otolaryngologists with appropriate strategies in the management of external auditory canal (EAC) carcinoma.

Methods: In the absence of randomized controlled trials, the consensus is based on expert opinions utilizing the Rand/UCLA appropriateness method [Fitch and Aguilar in The RAND/UCLA appropriateness method user's manual, RAND Corporation, Santa Monica, CA, 2001], drawing from existing literature and clinical experience.

Results: The management recommendations are structured around 12 key areas, including: definition and pathology, pathogenesis, clinical manifestations, work-up, tumor staging system, surgical management of primary tumor, surgical management of the parotid gland and the temporomandibular joint, lymph node metastasis, radiotherapy, chemotherapy, reconstruction, and follow-up.

Conclusion: Management strategies for EAC carcinoma rely on tumor extension and histopathological features. Surgical removal with free surgical margins or combination with radiotherapy, chemotherapy are most often the best options. Given the rarity of the disease, prospective, randomized, multi-institutional clinical trials should be designed to enable reliable comparisons of the outcomes of EAC carcinoma treatments, thereby providing evidence-based clinical data to establish widely accepted guidelines. It emphasizes the need for a multidisciplinary team to be involved in the management of EAC carcinoma, and regular follow-up should be implemented postoperatively.

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关于外耳道癌治疗的国际专家共识。

目的：本共识旨在为耳鼻喉科医生提供治疗外耳道癌的适当策略：方法：在缺乏随机对照试验的情况下，本共识基于专家意见，采用兰德/加州大学洛杉矶分校适当性方法[Fitch 和 Aguilar，见兰德/加州大学洛杉矶分校适当性方法用户手册，兰德公司，加利福尼亚州圣莫尼卡，2001 年]，并借鉴现有文献和临床经验：管理建议围绕 12 个关键领域展开，包括：定义和病理、发病机制、临床表现、检查、肿瘤分期系统、原发肿瘤的手术治疗、腮腺和颞下颌关节的手术治疗、淋巴结转移、放疗、化疗、重建和随访：结论：EAC 癌的治疗策略取决于肿瘤的扩展和组织病理学特征。手术切除、手术切缘游离或结合放疗、化疗通常是最佳选择。鉴于这种疾病的罕见性，应设计前瞻性、随机、多机构临床试验，以便对 EAC 癌的治疗结果进行可靠的比较，从而提供循证临床数据，制定广为接受的指南。报告强调，EAC 癌的治疗需要多学科团队的参与，术后应定期随访。

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来源期刊

European Archives of Oto-Rhino-Laryngology 医学-耳鼻喉科学

CiteScore

5.30

自引率

7.70%

发文量

537

审稿时长

2-4 weeks

期刊介绍： Official Journal of European Union of Medical Specialists – ORL Section and Board Official Journal of Confederation of European Oto-Rhino-Laryngology Head and Neck Surgery "European Archives of Oto-Rhino-Laryngology" publishes original clinical reports and clinically relevant experimental studies, as well as short communications presenting new results of special interest. With peer review by a respected international editorial board and prompt English-language publication, the journal provides rapid dissemination of information by authors from around the world. This particular feature makes it the journal of choice for readers who want to be informed about the continuing state of the art concerning basic sciences and the diagnosis and management of diseases of the head and neck on an international level. European Archives of Oto-Rhino-Laryngology was founded in 1864 as "Archiv für Ohrenheilkunde" by A. von Tröltsch, A. Politzer and H. Schwartze.