Real-world mobility recovery after hip fracture: secondary analyses of digital mobility outcomes from four randomized controlled trials.

IF 6 2区 医学 Q1 GERIATRICS & GERONTOLOGY
Monika Engdal, Kristin Taraldsen, Carl-Philipp Jansen, Raphael Simon Peter, Beatrix Vereijken, Clemens Becker, Jorunn Laegdheim Helbostad, Jochen Klenk
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引用次数: 0

Abstract

Background: The main focus of rehabilitation following hip fracture is to regain mobility.

Objectives: To estimate the progression of real-world mobility the first year after hip fracture using digital mobility outcomes.

Design: An exploratory, prospective cohort study with pooled data from four previously conducted clinical trials.

Setting and subjects: We combined data from the Trondheim Hip Fracture Trial and Eva-Hip Trial in Trondheim, Norway, and the PROFinD 1 and PROFinD 2 trials in Stuttgart and Heidelberg, Germany, resulting in a sample of 717 hip fracture patients aged ≥65 years.

Methods: Each of the trials assessed mobility using body-fixed sensors (activPAL) at three time points, collectively providing observations across the entire first year post-surgery. The following 24-h DMOs were calculated: total walking duration (minutes), maximum number of steps within a walking bout, and number of sit-to-stand-to-walk transfers. Continuous 1-year progression of the median, the 25th percentile, and the 75th percentile were estimated using quantile regression models with splines.

Results: The dataset contained 5909 observation days. The median daily total walking duration increased until 36 weeks post-surgery reaching 40 min; daily maximum number of steps within a walking bout increased during the first eight weeks and then stabilized at less than 100 steps; daily sit-to-stand-to-walk transfers reached a plateau after 6 weeks with less than 40 transfers.

Conclusions: The three DMOs progressed differently and attained plateau levels at varying times during the first year after hip fracture, indicating that these Digital Mobility Outcomes provide complementary information about different aspects of mobility recovery.

髋部骨折后真实世界的行动能力恢复:对四项随机对照试验的数字行动能力结果进行二次分析。
背景:髋部骨折后康复的主要重点是恢复活动能力:利用数字移动能力结果,估计髋部骨折后第一年实际移动能力的进展情况:设计:一项探索性、前瞻性队列研究,汇集了之前进行的四项临床试验的数据:我们合并了来自挪威特隆赫姆的特隆赫姆髋部骨折试验和 Eva-Hip 试验,以及德国斯图加特和海德堡的 PROFinD 1 和 PROFinD 2 试验的数据,得到了 717 名年龄≥65 岁的髋部骨折患者样本:每项试验都在三个时间点使用固定在身体上的传感器(activPAL)对活动能力进行评估,从而对术后第一年的活动能力进行观察。计算了以下 24 小时 DMOs:总步行时间(分钟)、一次步行的最大步数以及从坐到站再到步行的转移次数。使用带样条的量子回归模型估算了中位数、第 25 百分位数和第 75 百分位数的 1 年连续进展情况:数据集包含 5909 个观察日。每日总步行时间的中位数在术后36周之前一直在增加,达到40分钟;每日步行的最大步数在前8周增加,然后稳定在100步以下;每日从坐到站再到步行的转移在6周后达到高峰,转移次数少于40次:结论:在髋部骨折后的第一年中,三种数字移动能力指标的进展情况各不相同,并在不同时间达到了高原水平,这表明这些数字移动能力指标提供了有关移动能力恢复不同方面的互补信息。
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来源期刊
Age and ageing
Age and ageing 医学-老年医学
CiteScore
9.20
自引率
6.00%
发文量
796
审稿时长
4-8 weeks
期刊介绍: Age and Ageing is an international journal publishing refereed original articles and commissioned reviews on geriatric medicine and gerontology. Its range includes research on ageing and clinical, epidemiological, and psychological aspects of later life.
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