Misha Aftab Khan, Noor Alsammarraie, Alycia Christina Bellino, Yash Bharatkumar Patel, Karldon Iwuchukwu Nwaezeapu
{"title":"Coronary embolism and acute limb ischemia without pre-existing atrial fibrillation: Hunt for the hidden thrombus.","authors":"Misha Aftab Khan, Noor Alsammarraie, Alycia Christina Bellino, Yash Bharatkumar Patel, Karldon Iwuchukwu Nwaezeapu","doi":"10.1016/j.amjms.2024.10.006","DOIUrl":null,"url":null,"abstract":"<p><p>Coronary embolism (CE) is an infrequent etiology of myocardial infarction secondary to embolization of occlusive thrombi within the coronary arteries, typically arising in patients with pre-existing atrial fibrillation. Clinical presentation is similar to atherosclerotic myocardial infarction, however the condition is likely underrecognized. The simultaneous presence of other embolic manifestations may assist with diagnosis, although definitive therapy, medical or interventional, remains inconclusive. We aim to lower the threshold for clinical suspicion in the appropriate setting and promote assessment of predisposing embolic conditions once a tentative diagnosis of CE is established. In addition, we intend to highlight the need for focused refinement of the existing diagnostic criteria and further optimization of management guidelines for CE.</p>","PeriodicalId":94223,"journal":{"name":"The American journal of the medical sciences","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The American journal of the medical sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.amjms.2024.10.006","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Coronary embolism (CE) is an infrequent etiology of myocardial infarction secondary to embolization of occlusive thrombi within the coronary arteries, typically arising in patients with pre-existing atrial fibrillation. Clinical presentation is similar to atherosclerotic myocardial infarction, however the condition is likely underrecognized. The simultaneous presence of other embolic manifestations may assist with diagnosis, although definitive therapy, medical or interventional, remains inconclusive. We aim to lower the threshold for clinical suspicion in the appropriate setting and promote assessment of predisposing embolic conditions once a tentative diagnosis of CE is established. In addition, we intend to highlight the need for focused refinement of the existing diagnostic criteria and further optimization of management guidelines for CE.
冠状动脉栓塞(Cononary embolism,CE)是继发于冠状动脉内闭塞性血栓栓塞的心肌梗死的一种不常见病因,通常发生在原有心房颤动的患者身上。其临床表现与动脉粥样硬化性心肌梗死相似,但很可能未被充分认识。同时出现其他栓塞表现可能有助于诊断,但明确的药物或介入治疗仍无定论。我们的目标是在适当的情况下降低临床怀疑的门槛,并促进对 CE 初步诊断确定后的易发栓塞情况进行评估。此外,我们还希望强调有必要重点完善现有的诊断标准,并进一步优化 CE 的管理指南。