Optical coherence tomography angiography in cardiovascular disease

IF 5.6 2区医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS

Progress in cardiovascular diseases Pub Date : 2024-11-01 DOI:10.1016/j.pcad.2024.10.011

Oluwapeyibomi I. Runsewe , Sunil K. Srivastava , Sumit Sharma , Pulkit Chaudhury , W.H. Wilson Tang

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Abstract

Endothelial dysfunction and microvascular remodeling underly the development and progression of a host of cardiovascular disease (CVD). However, current methods to assess coronary epicardial microvascular function are invasive, time-intensive, and costly. Optical coherence tomography angiography (OCTA) is an established technology within ophthalmology that provides a quick, noninvasive assessment of vascular structures within the retina. As a growing body of evidence reveals strong associations between the retinal changes on OCTA and the development and progression of CVD, OCTA may indeed be a surrogate test for end-organ dysfunction. OCTA has potential to enhance diagnostic performance, refine cardiovascular risk assessment, strengthen prognostication, and ultimately, improve patient care. We explore the current literature on OCTA in cardiovascular diseases to summarize the clinical utility of retinal OCTA imaging and discuss next-generation cardiovascular applications.

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心血管疾病的光学相干断层血管造影。

内皮功能障碍和微血管重塑是一系列心血管疾病（CVD）发生和发展的基础。然而，目前评估冠状动脉心外膜微血管功能的方法都是侵入性的、耗时耗力且成本高昂。光学相干断层血管造影（OCTA）是眼科领域一项成熟的技术，可对视网膜内的血管结构进行快速、无创的评估。越来越多的证据表明，OCTA 所显示的视网膜变化与心血管疾病的发生和发展密切相关，因此 OCTA 可能确实是内脏器官功能障碍的替代检测方法。OCTA 具有提高诊断性能、完善心血管风险评估、加强预后判断以及最终改善患者护理的潜力。我们探讨了当前有关心血管疾病中 OCTA 的文献，总结了视网膜 OCTA 成像的临床实用性，并讨论了下一代心血管应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Progress in cardiovascular diseases 医学-心血管系统

CiteScore

10.90

自引率

6.60%

发文量

审稿时长

7 days

期刊介绍： Progress in Cardiovascular Diseases provides comprehensive coverage of a single topic related to heart and circulatory disorders in each issue. Some issues include special articles, definitive reviews that capture the state of the art in the management of particular clinical problems in cardiology.