Characteristics and survival of adults with differentiated thyroid cancer in a Peruvian hospital.

Q3 Medicine
Luz Morales-Concha, Iván Huamani-Linares, Katy Saihua-Palomino, Edward Luque Florez, Alexi Chávez Echevarría, Ramiro Jorge Tupayachi Palomino, Carlos Antonio Zea Nuñez, Christian R Mejia, Noé Atamari-Anahui
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引用次数: 0

Abstract

Background: Motivation for the study. There are few clinical and survival studies in Peru on thyroid cancer.

Background: Main findings. Between the years 2010 to 2020, differentiated thyroid cancer was more frequent in women with early-stage disease, but survival was lower at five years compared to reports from other countries.

Background: Implications. Thyroid cancer has increased in recent decades worldwide. It is important to have specialized and decentralized centers for the initial management and follow-up of these patients to avoid long-term complications or fatal outcomes and to have updated epidemiological information.

Background: This study aimed at studying the clinical and anatomopathological characteristics, treatment and survival of patients with differentiated thyroid cancer. A retrospective cohort study was conducted with data from 150 patients from a Peruvian hospital between the years 2010 to 2020. Characteristics and survival (Kaplan-Meier method) were described. The mean age was 48.3 years, 130 participants (86.7%) were women and the most frequent histologic type was papillary 94.6%. Of the participants, 74.2% had TNM stage I, 70.7% had total thyroidectomy and 68.7% received radioactive iodine. Overall survival at 5 years was 89.3%, being lower in those with TNM stage IV and higher in those who used radioactive iodine. In conclusion, in a hospital in Cusco, differentiated thyroid cancer was more frequent in women and survival was lower compared to reports from other countries.

秘鲁一家医院分化型甲状腺癌成人患者的特征和生存率。
背景:研究动机在秘鲁,关于甲状腺癌的临床和生存研究很少:主要发现。2010年至2020年期间,分化型甲状腺癌多发于早期女性,但与其他国家的报告相比,五年生存率较低:背景:影响。近几十年来,甲状腺癌在全球范围内呈上升趋势。为避免长期并发症或致命后果,以及掌握最新的流行病学信息,建立专业化和分散化的中心对这些患者进行初步治疗和随访非常重要:本研究旨在研究分化型甲状腺癌患者的临床和解剖病理特征、治疗和生存情况。这项回顾性队列研究收集了2010年至2020年间秘鲁一家医院150名患者的数据。研究描述了患者的特征和生存情况(卡普兰-梅耶法)。平均年龄为48.3岁,130名参与者(86.7%)为女性,最常见的组织学类型为乳头状,占94.6%。74.2%的患者处于TNM I期,70.7%的患者接受了甲状腺全切除术,68.7%的患者接受了放射性碘治疗。5年总生存率为89.3%,TNM分期为IV期的患者生存率较低,而使用放射性碘的患者生存率较高。总之,与其他国家的报告相比,在库斯科的一家医院中,女性患分化型甲状腺癌的比例较高,而生存率较低。
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来源期刊
Revista Peruana de Medicina de Experimental y Salud Publica
Revista Peruana de Medicina de Experimental y Salud Publica Medicine-Public Health, Environmental and Occupational Health
CiteScore
3.00
自引率
0.00%
发文量
57
审稿时长
12 weeks
期刊介绍: La Revista Peruana de Medicina Experimental y Salud Pública (RPMESP) es el órgano oficial de difusión científica del Instituto Nacional de Salud (INS) del Perú. Es una publicación arbitrada por pares, de periodicidad trimestral, de ámbito y difusión mundial, indizada en MEDLINE/Index Medicos, SCOPUS, EMBASE, SciELO Salud Pública y otras bases de datos internacionales. La RPMESP es distribuida en su versión impresa y electrónica, con acceso gratuito a texto completo. La RPMESP publica artículos referidos a temas del ámbito biomédico y de salud pública, resaltando aportes prácticos, que contribuyan a mejorar la situación de salud del país y de la región. Propicia el intercambio de la experiencia científica en salud entre instituciones y personas dedicadas a la investigación dentro y fuera del Perú a fin de promover el avance y la aplicación de la investigación en salud.
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