{"title":"Novel and emerging therapeutics for antimicrobial resistance: A brief review.","authors":"Raja Amir Hassan Kuchay","doi":"10.5582/ddt.2024.01063","DOIUrl":null,"url":null,"abstract":"<p><p>A pandemic known as anti-microbial resistance (AMR) poses a challenge to contemporary medicine. To stop AMR's rise and quick worldwide spread, urgent multisectoral intervention is needed. This review will provide insight on new and developing treatment approaches for AMR. Future therapy options may be made possible by the development of novel drugs that make use of developments in \"omics\" technology, artificial intelligence, and machine learning. Vaccines, immunoconjugates, antimicrobial peptides, monoclonal antibodies, and nanoparticles may also be intriguing options for treating AMR in the future. Combination therapy may potentially prove to be a successful strategy for combating AMR. To lessen the impact of AMR, ideas like drug repurposing, antibiotic stewardship, and the one health approach may be helpful.</p>","PeriodicalId":47494,"journal":{"name":"Drug Discoveries and Therapeutics","volume":" ","pages":"269-276"},"PeriodicalIF":1.9000,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Drug Discoveries and Therapeutics","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.5582/ddt.2024.01063","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/10/27 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0
Abstract
A pandemic known as anti-microbial resistance (AMR) poses a challenge to contemporary medicine. To stop AMR's rise and quick worldwide spread, urgent multisectoral intervention is needed. This review will provide insight on new and developing treatment approaches for AMR. Future therapy options may be made possible by the development of novel drugs that make use of developments in "omics" technology, artificial intelligence, and machine learning. Vaccines, immunoconjugates, antimicrobial peptides, monoclonal antibodies, and nanoparticles may also be intriguing options for treating AMR in the future. Combination therapy may potentially prove to be a successful strategy for combating AMR. To lessen the impact of AMR, ideas like drug repurposing, antibiotic stewardship, and the one health approach may be helpful.
抗微生物耐药性（AMR）这一流行病给当代医学带来了挑战。为了阻止 AMR 的上升和在全球范围内的迅速蔓延，需要采取紧急的多部门干预措施。本综述将深入探讨针对 AMR 的新的和正在开发的治疗方法。利用 "omics "技术、人工智能和机器学习的发展成果开发出的新型药物可能成为未来的治疗选择。疫苗、免疫结合剂、抗菌肽、单克隆抗体和纳米粒子也可能是未来治疗 AMR 的有趣选择。联合疗法有可能被证明是抗击 AMR 的成功策略。为了减轻 AMR 的影响，药物再利用、抗生素管理和一体健康法等理念可能会有所帮助。
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