Understanding the interplay between psoriatic arthritis and gout: "Psout".

IF 3.2 3区医学 Q2 RHEUMATOLOGY

Rheumatology International Pub Date : 2024-12-01 Epub Date: 2024-10-23 DOI:10.1007/s00296-024-05729-8

Alaa Sherri, Mohamad Mahdi Mortada, Joanna Makowska, Milena Sokolowska, Anna Lewandowska-Polak

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引用次数: 0

Abstract

The interplay between Psoriatic arthritis and Gout is a current diagnostic challenge faced by many physicians and researchers. We aimed at reviewing the coexistence of gout and its features such as hyperuricemia and deposition of monosodium urate crystals in patients with psoriatic arthritis (PsA). We also focused on a brief presentation of the pathophysiology underneath the interplay between PsA and gout, and ultimately on recommendation of approaches for the differential diagnosis. The literature search for this narrative review was conducted using PubMed and Medline and after retrieving and screening the references, articles were selected according to the inclusion and exclusion criteria. Part of the assessed studies reported the coexistence of PsA and gout (Psout) and its association with several clinical outcomes among affected patients. Other studies stressed incidences of misdiagnosis of gout with PsA and vice versa. Additionally, the presence of hyperuricemia in PsA patients could interfere with the patient's characteristics and outcomes of their treatment. Further research on the assessment and clinical course of Psout is required to develop an official protocol for its diagnosis and treatment.

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了解银屑病关节炎与痛风之间的相互作用："Psout"。

银屑病关节炎与痛风之间的相互作用是许多医生和研究人员目前面临的诊断难题。我们的目的是回顾银屑病关节炎（PsA）患者同时存在痛风及其特征（如高尿酸血症和单钠尿酸盐结晶沉积）的情况。我们还重点简要介绍了 PsA 和痛风之间相互作用的病理生理学，并最终推荐了鉴别诊断的方法。本叙事性综述的文献检索是通过 PubMed 和 Medline 进行的，在检索和筛选参考文献后，根据纳入和排除标准对文章进行了筛选。部分被评估的研究报告了PsA与痛风（Psout）并存的情况及其与受影响患者若干临床结果的关联。其他研究强调了痛风与PsA的误诊率，反之亦然。此外，PsA 患者出现高尿酸血症可能会影响患者的特征和治疗效果。需要进一步研究痛风的评估和临床过程，以制定正式的诊断和治疗方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Rheumatology International 医学-风湿病学

CiteScore

7.30

自引率

5.00%

发文量

191

审稿时长

16. months

期刊介绍： RHEUMATOLOGY INTERNATIONAL is an independent journal reflecting world-wide progress in the research, diagnosis and treatment of the various rheumatic diseases. It is designed to serve researchers and clinicians in the field of rheumatology. RHEUMATOLOGY INTERNATIONAL will cover all modern trends in clinical research as well as in the management of rheumatic diseases. Special emphasis will be given to public health issues related to rheumatic diseases, applying rheumatology research to clinical practice, epidemiology of rheumatic diseases, diagnostic tests for rheumatic diseases, patient reported outcomes (PROs) in rheumatology and evidence on education of rheumatology. Contributions to these topics will appear in the form of original publications, short communications, editorials, and reviews. "Letters to the editor" will be welcome as an enhancement to discussion. Basic science research, including in vitro or animal studies, is discouraged to submit, as we will only review studies on humans with an epidemological or clinical perspective. Case reports without a proper review of the literatura (Case-based Reviews) will not be published. Every effort will be made to ensure speed of publication while maintaining a high standard of contents and production. Manuscripts submitted for publication must contain a statement to the effect that all human studies have been reviewed by the appropriate ethics committee and have therefore been performed in accordance with the ethical standards laid down in an appropriate version of the 1964 Declaration of Helsinki. It should also be stated clearly in the text that all persons gave their informed consent prior to their inclusion in the study. Details that might disclose the identity of the subjects under study should be omitted.