Lignin: An Adaptable Biodegradable Polymer Used in Different Formulation Processes.

IF 4.3 3区医学 Q2 CHEMISTRY, MEDICINAL

Pharmaceuticals Pub Date : 2024-10-21 DOI:10.3390/ph17101406

Andreea Creteanu, Claudiu N Lungu, Mirela Lungu

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引用次数: 0

Abstract

Introduction: LIG is a biopolymer found in vascular plant cell walls that is created by networks of hydroxylated and methoxylated phenylpropane that are randomly crosslinked. Plant cell walls contain LIG, a biopolymer with significant potential for usage in modern industrial and pharmaceutical applications. It is a renewable raw resource. The plant is mechanically protected by this substance, which may increase its durability. Because it has antibacterial and antioxidant qualities, LIG also shields plants from biological and chemical challenges from the outside world. Researchers have done a great deal of work to create new materials and substances based on LIG. Numerous applications, including those involving antibacterial agents, antioxidant additives, UV protection agents, hydrogel-forming molecules, nanoparticles, and solid dosage forms, have been made with this biopolymer.

Methods: For this review, a consistent literature screening using the Pubmed database from 2019-2024 has been performed.

Results: The results showed that there is an increase in interest in lignin as an adaptable biomolecule. The most recent studies are focused on the biosynthesis and antimicrobial properties of lignin-derived molecules. Also, the use of lignin in conjunction with nanostructures is actively explored.

Conclusions: Overall, lignin is a versatile molecule with multiple uses in industry and medical science.

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木质素：木质素：一种可在不同配方工艺中使用的可生物降解聚合物。

简介LIG 是维管植物细胞壁中的一种生物聚合物，由羟基化和甲氧基化的苯基丙烷网络随机交联而成。植物细胞壁中含有 LIG，这种生物聚合物在现代工业和医药应用中具有巨大的应用潜力。它是一种可再生的原材料。植物受到这种物质的机械保护，可以提高其耐久性。由于 LIG 具有抗菌和抗氧化特性，它还能保护植物免受来自外界的生物和化学挑战。研究人员已经做了大量工作，在 LIG 的基础上创造出新的材料和物质。这种生物聚合物已被广泛应用，包括抗菌剂、抗氧化添加剂、紫外线防护剂、水凝胶形成分子、纳米颗粒和固体制剂：本综述使用 Pubmed 数据库对 2019-2024 年间的文献进行了连贯筛选：结果表明，人们对木质素这种适应性强的生物大分子的兴趣与日俱增。最近的研究主要集中在木质素衍生分子的生物合成和抗菌特性方面。此外，人们还积极探索如何将木质素与纳米结构结合使用：总之，木质素是一种用途广泛的分子，在工业和医学领域具有多种用途。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pharmaceuticals Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science

CiteScore

6.10

自引率

4.30%

发文量

1332

审稿时长

6 weeks

期刊介绍： Pharmaceuticals (ISSN 1424-8247) is an international scientific journal of medicinal chemistry and related drug sciences.Our aim is to publish updated reviews as well as research articles with comprehensive theoretical and experimental details. Short communications are also accepted; therefore, there is no restriction on the maximum length of the papers.