Topical Timolol for Treatment of Spider Angiomas in Children: A Case Series.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-10-22 DOI:10.1111/pde.15788

Marie-Chantal Caussade, Griffin Stockton Hogrogian, Albert C Yan

引用次数: 0

Abstract

We report five cases of spider angiomas in children treated topically with timolol 0.5% (ophthalmic solution or gel-forming solution), for 6 months. Parents and patients were advised to apply one drop twice daily. Four of them showed either partial (2) or complete response (2) and only one patient had no clinical change. No adverse effects were reported. This pilot case series shows that topical timolol may prove useful as a noninvasive, available and well-tolerated treatment option for spider angiomas in children who seek a treatment alternative to pulsed dye laser.

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外用噻吗洛尔治疗儿童蛛状血管瘤：病例系列。

我们报告了五例蛛状血管瘤患儿，他们均接受了噻吗洛尔 0.5%（眼用溶液或凝胶状溶液）的局部治疗，疗程长达 6 个月。建议家长和患者每天两次滴用一滴噻吗洛尔。其中四名患者出现部分反应（2 例）或完全反应（2 例），只有一名患者没有临床变化。无不良反应报告。这一试验性病例系列表明，对于寻求脉冲染料激光治疗方法替代方案的儿童蜘蛛状血管瘤患者，局部噻吗洛尔可能被证明是一种非侵入性、可用且耐受性良好的治疗方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.