Skin Imaging of Juvenile Xanthogranuloma: In Vivo Diagnosis by Line-Field Confocal Optical Coherence Tomography.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-10-24 DOI:10.1111/pde.15786

Gerardo Palmisano, Simone Cappilli, Enrico Bocchino, Alessandro Di Stefani, Ketty Peris

引用次数: 0

Abstract

A 15-year-old boy presented with a yellowish, asymptomatic nodule on the left forearm, which developed in the last year. A diagnosis of juvenile xanthogranuloma was confirmed with histopathology. Line-field confocal optical coherence tomography (LC-OCT), a new skin imaging technique, was performed prior to surgery, showing a strong correspondence with histopathological sections. As juvenile xanthogranuloma is a benign disorder of the pediatric age, LC-OCT may represent an alternative to surgery for achieving a fast diagnosis in uncertain cases.

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幼年黄疽瘤的皮肤成像：通过线场共聚焦光学相干断层扫描进行体内诊断。

一名 15 岁的男孩左前臂上长了一个淡黄色的无症状结节，去年才开始发病。经组织病理学检查，确诊为幼年黄疽瘤。手术前进行了线场共焦光学相干断层扫描（LC-OCT），这是一种新的皮肤成像技术，显示与组织病理切片非常吻合。由于幼年黄疽瘤是儿科良性疾病，LC-OCT可作为手术的替代方法，在不确定的病例中实现快速诊断。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.