Industrial Genotoxicology Group (IGG): 36th Annual Meeting Report.

IF 2.5 4区 医学 Q3 GENETICS & HEREDITY
Mutagenesis Pub Date : 2024-10-24 DOI:10.1093/mutage/geae025
Darren Kidd, Ian Crooks, Angela Saccardo, David J Ponting, Grace Kocks, Raj Gandhi, Dean Thomas, Emily Pass, Anthony Lynch, George Johnson, Paul Fowler, Amy Wilson
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引用次数: 0

Abstract

The proceedings of the 36th annual meeting of the Industrial Genotoxicology Group (IGG) are shared here. The meeting held at Lhasa Limited, Leeds, UK on 28th November 2023, focussed two aspects; New Approach Methodologies (NAM's), including those for the assessment of non-standard modalities such as gas-vapour assessments and nanomaterials, and addressing the regulatory challenges associated with understanding the genotoxic and carcinogenic potential of N-nitrosamines and N-nitrosamine impurities. New approach methodologies, such as error-corrected sequencing and enhanced Ames tests that may help address these challenges were also discussed.

工业遗传毒理学小组(IGG):第 36 届年会报告。
在此分享工业遗传毒理学组(IGG)第 36 届年会的会议记录。会议于 2023 年 11 月 28 日在英国利兹的拉萨有限公司举行,重点讨论了两个方面的问题:新方法(NAM),包括用于评估气体-蒸汽评估和纳米材料等非标准模式的方法,以及应对与了解 N-亚硝胺和 N-亚硝胺杂质的遗传毒性和致癌潜力相关的监管挑战。会上还讨论了有助于应对这些挑战的新方法,如误差校正测序和增强型艾姆斯试验。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Mutagenesis
Mutagenesis 生物-毒理学
CiteScore
5.90
自引率
3.70%
发文量
22
审稿时长
6-12 weeks
期刊介绍: Mutagenesis is an international multi-disciplinary journal designed to bring together research aimed at the identification, characterization and elucidation of the mechanisms of action of physical, chemical and biological agents capable of producing genetic change in living organisms and the study of the consequences of such changes.
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