Diagnostic Test Accuracy of Contrast-Enhanced Ultrasound With Sonazoid for Assessment of Focal Liver Lesions: A Systematic Review and Meta-Analysis.

IF 1.2 4区医学 Q3 ACOUSTICS

Journal of Clinical Ultrasound Pub Date : 2024-10-23 DOI:10.1002/jcu.23879

Yongqing Tang, Shun-Ichi Sasaki, Joshua Hawley, Aurélie Peillon, Anders Sjöström, Adolfo Fuentes-Alburo, Francois Tranquart

引用次数: 0

Abstract

This meta-analysis examined the diagnostic accuracy of Sonazoid-enhanced ultrasonography (SZ-CEUS) in discriminating malignant from benign focal liver lesions (FLLs) and HCC from non-HCC FLLs. Finding relevant studies required a rigorous PubMed, EMBASE, and other database search. To distinguish malignant from benign FLLs, SZ-CEUS had a pooled sensitivity of 94% (95% CI: 0.91-0.95) and specificity of 84% (95%: 0.78-0.89). HCC distinction had 83% sensitivity and 96% specificity (95% CI: 0.80-0.85 and 0.95-0.97). SZ-CEUS accurately distinguishes malignant from benign FLLs and HCC from non-HCC lesions, especially smaller HCC lesions.

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使用 Sonazoid 的对比增强超声波评估肝脏病灶的诊断测试准确性：系统回顾与元分析》。

这项荟萃分析研究了Sonazoid增强超声造影（SZ-CEUS）在区分恶性和良性肝局灶病变（FLLs）以及HCC和非HCC FLLs方面的诊断准确性。要找到相关研究，需要对PubMed、EMBASE和其他数据库进行严格检索。在区分恶性和良性FLL方面，SZ-CEUS的总体敏感性为94%（95% CI：0.91-0.95），特异性为84%（95%：0.78-0.89）。区分 HCC 的敏感性为 83%，特异性为 96%（95% CI：0.80-0.85 和 0.95-0.97）。SZ-CEUS能准确区分恶性和良性FLL以及HCC和非HCC病变，尤其是较小的HCC病变。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Clinical Ultrasound 医学-核医学

CiteScore

1.90

自引率

0.00%

发文量

248

审稿时长

6 months

期刊介绍： The Journal of Clinical Ultrasound (JCU) is an international journal dedicated to the worldwide dissemination of scientific information on diagnostic and therapeutic applications of medical sonography. The scope of the journal includes--but is not limited to--the following areas: sonography of the gastrointestinal tract, genitourinary tract, vascular system, nervous system, head and neck, chest, breast, musculoskeletal system, and other superficial structures; Doppler applications; obstetric and pediatric applications; and interventional sonography. Studies comparing sonography with other imaging modalities are encouraged, as are studies evaluating the economic impact of sonography. Also within the journal''s scope are innovations and improvements in instrumentation and examination techniques and the use of contrast agents. JCU publishes original research articles, case reports, pictorial essays, technical notes, and letters to the editor. The journal is also dedicated to being an educational resource for its readers, through the publication of review articles and various scientific contributions from members of the editorial board and other world-renowned experts in sonography.