Epidemiological profile and clinical characteristics of ocular and periocular tumors in North and Central India.

IF 2.1 4区 医学 Q2 OPHTHALMOLOGY
Chhavi Gupta, Narendra Patidar, Himanshu Gaikwad, Mihir Mishra, Sima Das
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引用次数: 0

Abstract

Purpose: To describe the epidemiological profile and clinical characteristics of ocular and periocular tumors in patients presenting to three tertiary care referral centers in North and Central India.

Methods: Hospital-based consortium study.

Settings and design: Retrospective, descriptive, observational study.

Results: A total of 3184 patients were diagnosed with 3557 ocular and periocular tumors over 11 years from 2010 to 2021. Of these, 2395 (67.33%) were benign, 84 (2.36%) were premalignant, and 1078 (30.30%) were malignant. The most common location was the ocular surface (n = 1294, 37.09%), followed by the eyelid (n = 1185, 33.97%), intraocular (n = 624, 17.88%), and orbit (n = 454, 13.01%). The most common tumors were retinoblastoma (n = 483, 13.57%), ocular surface squamous neoplasia (OSSN) (n = 301, 8.46%), and dermoid cyst (n = 167, 4.69%). In the pediatric age group, retinoblastoma was the most common tumor (n = 483, 13.57%), while in adults, it was OSSN (n = 301, 8.46%). The stage at presentation for malignant tumors was divided into in-situ (57.14%), local spread (8.16%), and metastasis (32.83%). For specific tumor locations, the stages were 78.83%, 17.51%, and 2.18%, respectively, for eyelid tumors; 51.76%, 27.05%, and 17.64%, respectively, for orbital tumors; 88.37%, 5.81%, and 5.19%, respectively for ocular surface tumors; and 35.71%, 14.15%, and 50.28%, respectively, for intraocular tumors.

Conclusions: Identifying the epidemiological characteristics of ocular and periocular tumors will aid in early diagnosis and timely intervention. Intraocular tumors showed delayed diagnosis, advanced stages at presentation, and required patients to travel longer distances for treatment, indicating the need for strengthened diagnostic and treatment facilities to improve access to care.

印度北部和中部眼部和眼周肿瘤的流行病学概况和临床特征。
目的:描述在印度北部和中部三家三级医疗转诊中心就诊的眼部和眼周肿瘤患者的流行病学概况和临床特征:设置和设计:回顾性、描述性、观察性研究:结果:从2010年到2021年的11年间,共有3184名患者被诊断患有3557种眼部和眼周肿瘤。其中,2395例(67.33%)为良性,84例(2.36%)为癌前病变,1078例(30.30%)为恶性。最常见的部位是眼表(1294 例,37.09%),其次是眼睑(1185 例,33.97%)、眼内(624 例,17.88%)和眼眶(454 例,13.01%)。最常见的肿瘤是视网膜母细胞瘤(483 例,13.57%)、眼表鳞状上皮肿瘤(301 例,8.46%)和皮样囊肿(167 例,4.69%)。在儿童年龄组中,视网膜母细胞瘤是最常见的肿瘤(483 人,13.57%),而在成人中,视网膜母细胞瘤是最常见的肿瘤(301 人,8.46%)。恶性肿瘤的发病分期分为原位(57.14%)、局部扩散(8.16%)和转移(32.83%)。就肿瘤的具体部位而言,眼睑肿瘤的分期率分别为78.83%、17.51%和2.18%;眼眶肿瘤的分期率分别为51.76%、27.05%和17.64%;眼表肿瘤的分期率分别为88.37%、5.81%和5.19%;眼内肿瘤的分期率分别为35.71%、14.15%和50.28%:结论:确定眼部和眼周肿瘤的流行病学特征有助于早期诊断和及时干预。眼内肿瘤显示出诊断延迟、发病时已是晚期、患者需要长途跋涉接受治疗等特点,这表明有必要加强诊断和治疗设施,以改善医疗服务的可及性。
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来源期刊
CiteScore
3.80
自引率
19.40%
发文量
1963
审稿时长
38 weeks
期刊介绍: Indian Journal of Ophthalmology covers clinical, experimental, basic science research and translational research studies related to medical, ethical and social issues in field of ophthalmology and vision science. Articles with clinical interest and implications will be given preference.
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