Effect of teduglutide, a glucagon-like peptide-2 analog, in eosinophilic enterocolitis: a case report.

IF 2.1 3区医学 Q2 PEDIATRICS

Frontiers in Pediatrics Pub Date : 2024-10-08 eCollection Date: 2024-01-01 DOI:10.3389/fped.2024.1457824

Shoko Ogawa, Ken-Ichiro Konishi, Kiyoshi Tanaka, Hajime Takayasu, Yoshimasa Uematsu, Takashi Ito, Hiroyuki Takahashi, Yusuke Kumamoto

引用次数: 0

Abstract

We successfully treated a 4-year-old girl with short bowel syndrome and eosinophilic enterocolitis with teduglutide, a glucagon-like peptide-2 analog. Her eosinophilic enterocolitis was cured without relapse, and we were able to increase enteral nutrition. We found that teduglutide had an anti-inflammatory effect in this patient with eosinophilic gastrointestinal disease associated with short bowel syndrome. This report is the first to describe use of teduglutide in the treatment of eosinophilic gastrointestinal disease.

查看原文本刊更多论文

胰高血糖素样肽-2 类似物 Teduglutide 对嗜酸性粒细胞性小肠结肠炎的疗效：一份病例报告。

我们使用胰高血糖素样肽-2 类似物 Teduglutide 成功治疗了一名患有短肠综合征和嗜酸性粒细胞性小肠结肠炎的 4 岁女孩。她的嗜酸性粒细胞性小肠结肠炎治愈了，而且没有复发，我们还增加了肠内营养。我们发现，在这名嗜酸性粒细胞胃肠病伴短肠综合征的患者身上，泰度鲁肽具有抗炎作用。本报告首次描述了使用泰度鲁肽治疗嗜酸性粒细胞性胃肠病的情况。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Frontiers in Pediatrics Medicine-Pediatrics, Perinatology and Child Health

CiteScore

3.60

自引率

7.70%

发文量

2132

审稿时长

14 weeks

期刊介绍： Frontiers in Pediatrics (Impact Factor 2.33) publishes rigorously peer-reviewed research broadly across the field, from basic to clinical research that meets ongoing challenges in pediatric patient care and child health. Field Chief Editors Arjan Te Pas at Leiden University and Michael L. Moritz at the Children''s Hospital of Pittsburgh are supported by an outstanding Editorial Board of international experts. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. Frontiers in Pediatrics also features Research Topics, Frontiers special theme-focused issues managed by Guest Associate Editors, addressing important areas in pediatrics. In this fashion, Frontiers serves as an outlet to publish the broadest aspects of pediatrics in both basic and clinical research, including high-quality reviews, case reports, editorials and commentaries related to all aspects of pediatrics.