Time trends and advances in the management of global, regional, and national diabetes in adolescents and young adults aged 10-24 years, 1990-2021: analysis for the global burden of disease study 2021.

IF 3.4 3区医学 Q2 ENDOCRINOLOGY & METABOLISM

Diabetology & Metabolic Syndrome Pub Date : 2024-10-26 DOI:10.1186/s13098-024-01491-w

Yan Liu, Shenhang Yao, Xiangxiang Shan, Yuting Luo, Lulu Yang, Wu Dai, Ben Hu

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引用次数: 0

Abstract

Background: Estimation of global diabetes burden in adolescents and young adults (10-24 years) from 1990 to 2021.

Methods: Data were extracted from the 2021 Global Burden of Disease Study. Joinpoint regression analysis was employed to examine trends over the past 30 years, frontier analysis identified regions with potential for improvement, and the slope index of inequality and the relative concentration index were used to assess health inequalities.

Results: From 1990 to 2021, the age-standardized prevalence rates (ASPR) and age-standardized disability-adjusted life years rates (ASDR) of diabetes in adolescents and young adults increased globally, while age-standardized death rates (ASMR) remained stable. Oceania bore the highest burden regionally, East Asia experienced the fastest rise in ASPR and ASDR, and High-income Asia Pacific saw the most significant decrease in ASMR. Among 204 countries, Marshall Island and Hait reported the highest ASPR, ASDR, and ASMR in 2021. Health inequality analysis confirmed that the burden was concentrated in countries with lower Socio-Demographic Index (SDI). Frontier analysis showed that ASMR and ASDR were negatively correlated with SDI, with Yemen and Honduras, which have lower socio-demographic indices, exhibiting more smaller overall differences from frontier boundaries.

Conclusions: The analysis revealed a sharp increase in the global ASPR and ASDR of diabetes in adolescents and young adults. Additionally, the disease burden is typically concentrated in countries with lower SDI, highlighting an urgent need for governments to develop flexible health policies to mitigate the escalating threat of diabetes in this demographic.

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1990-2021 年全球、地区和国家 10-24 岁青少年糖尿病管理的时间趋势和进展：2021 年全球疾病负担研究分析。

背景：估算1990年至2021年全球青少年和年轻成人（10-24岁）的糖尿病负担：方法：从《2021 年全球疾病负担研究》中提取数据。方法：数据摘自《2021 年全球疾病负担研究》，采用连接点回归分析研究过去 30 年的趋势，前沿分析确定有改善潜力的地区，不平等斜率指数和相对集中指数用于评估健康不平等：从1990年到2021年，全球青少年糖尿病的年龄标准化患病率（ASPR）和年龄标准化残疾调整生命年率（ASDR）均有所上升，而年龄标准化死亡率（ASMR）则保持稳定。大洋洲地区的负担最重，东亚地区的青少年和青年糖尿病调整生命年率和年龄标准化死亡率上升最快，而亚太地区高收入国家的年龄标准化死亡率下降最为显著。在 204 个国家中，马绍尔群岛和海地报告的 2021 年 ASPR、ASDR 和 ASMR 最高。健康不平等分析证实，负担主要集中在社会人口指数（SDI）较低的国家。前沿分析表明，ASMR 和 ASDR 与 SDI 呈负相关，社会人口指数较低的也门和洪都拉斯与前沿边界的总体差异较小：分析表明，全球青少年和年轻成年人糖尿病的 ASPR 和 ASDR 急剧增加。此外，疾病负担通常集中在社会人口指数较低的国家，这表明各国政府迫切需要制定灵活的卫生政策，以减轻糖尿病对这一人群不断升级的威胁。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diabetology & Metabolic Syndrome ENDOCRINOLOGY & METABOLISM-

CiteScore

6.20

自引率

0.00%

发文量

170

审稿时长

7.5 months

期刊介绍： Diabetology & Metabolic Syndrome publishes articles on all aspects of the pathophysiology of diabetes and metabolic syndrome. By publishing original material exploring any area of laboratory, animal or clinical research into diabetes and metabolic syndrome, the journal offers a high-visibility forum for new insights and discussions into the issues of importance to the relevant community.