Exposure to microplastics contaminated with pharmaceuticals and personal care products: Histological effects on Ucides cordatus.

IF 8.2 1区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Science of the Total Environment Pub Date : 2024-12-15 Epub Date: 2024-10-20 DOI:10.1016/j.scitotenv.2024.177042

Letícia Fernanda da Silva, Caio Rodrigues Nobre, Beatriz Barbosa Moreno, Camilo Dias Seabra Pereira, Alexandre Rodrigo Nascimento Gonçalves, Nathalia Sales Soares do Nascimento, Gabriela Pustiglione Marinsek, Renata de Britto Mari, Fábio Ruiz Simões, José Hérelis Carnaúba, Rodrigo Brasil Choueri, Paloma Kachel Gusso-Choueri, Augusto Cesar

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引用次数: 0

Abstract

Pharmaceuticals and personal care products (PPCPs) are known to interact with microplastics (MPs) in aquatic environments, with substances such as the antimicrobial triclosan (TCS) and the synthetic hormone 17α-ethinylestradiol (EE2) being prevalent. These persistent contaminants are linked to toxic effects in aquatic organisms. This study aimed to investigate histological and morphometric changes in the gills of Ucides cordatus exposed to microplastics alone and microplastics contaminated with PPCPs. The experimental design included four treatment groups: 1) control (C), 2) virgin microplastics (MP), 3) microplastics fortified with triclosan (MPT), and 4) microplastics fortified with 17α-ethinylestradiol (MPE), with exposure durations of 3 or 7 days. Significant differences were observed in the histopathological indices for treatments with PPCP-fortified microplastics at 3 days (MPT and MPE) and 7 days (MPT). Notable pathologies included necrosis, fibrosis, and circulatory disorders. Exposure duration was significantly associated with morphometric changes, including secondary lamellar width in MPT and secondary lamellar length in MPE. These findings indicate that exposure to microplastics contaminated with PPCPs may impair the osmoregulatory and respiratory functions of Ucides cordatus.

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接触受药品和个人护理产品污染的微塑料：脐带乌贼的组织学影响。

众所周知，药品和个人护理产品（PPCPs）会与水生环境中的微塑料（MPs）发生相互作用，其中抗菌剂三氯生（TCS）和合成激素 17α- 乙炔雌二醇（EE2）等物质最为普遍。这些持久性污染物与水生生物的毒性效应有关。本研究旨在调查单独暴露于微塑料和被 PPCPs 污染的微塑料的脐带鱼鳃的组织学和形态计量学变化。实验设计包括四个处理组：1）对照组（C）；2）原始微塑料组（MP）；3）添加三氯生的微塑料组（MPT）；4）添加 17α- 乙炔基雌二醇的微塑料组（MPE）。在接触 3 天（MPT 和 MPE）和 7 天（MPT）的情况下，观察到使用经 PPCP 强化的微塑料的组织病理学指数存在显著差异。显著的病理变化包括坏死、纤维化和循环障碍。接触时间长短与形态变化（包括 MPT 中的次生薄片宽度和 MPE 中的次生薄片长度）密切相关。这些研究结果表明，接触受多环芳烃污染的微塑料可能会损害脊索动物的渗透调节和呼吸功能。

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来源期刊

Science of the Total Environment 环境科学-环境科学

CiteScore

17.60

自引率

10.20%

发文量

8726

审稿时长

2.4 months

期刊介绍： The Science of the Total Environment is an international journal dedicated to scientific research on the environment and its interaction with humanity. It covers a wide range of disciplines and seeks to publish innovative, hypothesis-driven, and impactful research that explores the entire environment, including the atmosphere, lithosphere, hydrosphere, biosphere, and anthroposphere. The journal's updated Aims & Scope emphasizes the importance of interdisciplinary environmental research with broad impact. Priority is given to studies that advance fundamental understanding and explore the interconnectedness of multiple environmental spheres. Field studies are preferred, while laboratory experiments must demonstrate significant methodological advancements or mechanistic insights with direct relevance to the environment.