A Randomized Controlled Trial of Adding Deep Parasternal Intercostal Plane Block to Interpectoral-Pectoserratus Plane Block in Breast Cancer Surgery.

Bin Gu,Zhang-Xiang Huang,Hui-Dan Zhou,Yan-Hong Lian,Shuang He,Meng Ge,Hui-Fang Jiang
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Abstract

BACKGROUND The interpectoral-pectoserratus plane block is expected to anesthetize the lateral breast, but it is unclear whether the deep parasternal intercostal plane block may enhance recovery by providing analgesia to the medial breast. METHODS Patients undergoing breast cancer surgery were randomly assigned to receive either the interpectoral-pectoserratus block (single block) or interpectoral-pectoserratus combined with deep parasternal intercostal block (combined block). The primary outcome was the quality of recovery-15 questionnaire score assessed at 24 hours postoperatively. Secondary measures included dermatomal block assessment, pain severity, opioid consumption, opioid-related adverse events, hospital length of stay, and chronic postsurgical pain at 3 months after surgery. RESULTS One hundred and sixteen patients were recruited, 58 in the single block group and 58 in the combined block group. There was no important difference in the 24-hour quality of recovery scores with mean (standard deviation [SD]) 123.6 (6.3) in the single block group and 123.2 (7.1) in the combined block group (mean difference, 0.4; 95% confidence interval [CI], -2.0 to 2.9; P =.731). There was greater dermatomal block on medial breast in the combined block group. There were no differences in other secondary outcomes. CONCLUSIONS Addition of deep parasternal intercostal plane block was not superior to interpectoral-pectoserratus plane block alone for the quality of recovery in patients undergoing breast cancer surgery.
在乳腺癌手术中增加胸骨旁肋间深平面阻滞与胸骨胸肌间平面阻滞的随机对照试验》(Randomized Controlled Trial of Adding Deep Parasternal Intercostal Plane Block to Interpectoral-Pectoserratus Plane Block in Breast Cancer Surgery)。
方法对接受乳腺癌手术的患者进行随机分配,让他们接受胸骨间-胸肌平面阻滞(单一阻滞)或胸骨间-胸肌平面联合胸骨深旁-肋间阻滞(联合阻滞)。主要结果是在术后 24 小时评估恢复质量-15 问卷得分。次要指标包括皮肤阻滞评估、疼痛严重程度、阿片类药物消耗量、阿片类药物相关不良事件、住院时间以及术后3个月的慢性术后疼痛。单一阻滞组和联合阻滞组的 24 小时恢复质量评分没有明显差异,分别为 123.6(6.3)和 123.2(7.1)(平均差异为 0.4;95% 置信区间 [CI],-2.0 至 2.9;P =.731)。联合阻滞组的乳房内侧皮下阻滞更大。结论就乳腺癌手术患者的恢复质量而言,增加胸骨旁肋间深面阻滞并不优于单独的胸阔肌-胸肌平面阻滞。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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