Limiting the use and misuse of liothyronine in hypothyroidism

IF 3.7 3区医学 Q2 CHEMISTRY, MEDICINAL

Chemical Research in Toxicology Pub Date : 2024-10-24 DOI:10.1038/s41574-024-01055-y

Laszlo Hegedüs, Endre Vezekenyi Nagy, Enrico Papini, Petros Perros

引用次数: 0

Abstract

Liothyronine treatment for some patients with hypothyroidism has preoccupied academics, clinicians and patients for decades, and is a controversial topic in thyroidology. Persistent symptoms are at the heart of this discourse and, contrary to scientific evidence, liothyronine use is increasingly common. Aetiologies and interventions beyond thyroid dysregulation and pharmacological approaches must be pursued.

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限制甲状腺功能减退症患者使用和滥用甲状腺素

数十年来，学术界、临床医生和患者一直在关注针对部分甲减患者的甲状腺素治疗，这也是甲状腺学中一个颇具争议的话题。持续性症状是这一讨论的核心，与科学证据相反，使用甲状腺素的情况越来越普遍。除了甲状腺失调和药物治疗方法之外，我们还必须寻求其他病因和干预措施。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Chemical Research in Toxicology 医学-毒理学

CiteScore

7.90

自引率

7.30%

发文量

215

审稿时长

3.5 months

期刊介绍： Chemical Research in Toxicology publishes Articles, Rapid Reports, Chemical Profiles, Reviews, Perspectives, Letters to the Editor, and ToxWatch on a wide range of topics in Toxicology that inform a chemical and molecular understanding and capacity to predict biological outcomes on the basis of structures and processes. The overarching goal of activities reported in the Journal are to provide knowledge and innovative approaches needed to promote intelligent solutions for human safety and ecosystem preservation. The journal emphasizes insight concerning mechanisms of toxicity over phenomenological observations. It upholds rigorous chemical, physical and mathematical standards for characterization and application of modern techniques.