[Retracted] Zearalenone regulates endometrial stromal cell apoptosis and migration via the promotion of mitochondrial fission by activation of the JNK/Drp1 pathway.

IF 3.4 3区 医学 Q2 MEDICINE, RESEARCH & EXPERIMENTAL
Molecular medicine reports Pub Date : 2024-12-01 Epub Date: 2024-10-18 DOI:10.3892/mmr.2024.13363
Huixiang Wang, Xiaoli Zhao, Chengxiang Ni, Yuyang Dai, Yan Guo
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引用次数: 0

Abstract

Following the publication of this article, a concerned reader drew to the Editor's attention that the experimental design of the western blot assay experiments portrayed in Fig. 5A on p. 7804, and the overall organization of this figure, may have been flawed, as mitochondrial and cytosolic proteins were featured in the figure with only one set of supporting control western blot data; in this scenario, the proteins would necessarily have needed to have been obtained from two separate cell samples in different experiments, and blotted on to separate gels. Moreover, there was also a concern that certain of the gels featured possible breaks in their continuity/splicing events, such that the protein bands in the figure were not shown consecutively, as they would have appeared, in the affected slices. After having conducted an internal investigation, the Editor of Molecular Medicine Reports agrees with the reader that there were anomalies associated with the presentation of Fig. 5. Therefore, on the grounds of a lack of confidence in the presented data, the Editor has decided that the article should be retracted from the publication. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused, and we also thank the reader for bringing this matter to our attention. [Molecular Medicine Reports 17: 7797‑7806, 2018; DOI: 10.3892/mmr.2018.8823].

[撤稿】玉米赤霉烯酮通过激活 JNK/Drp1 通路促进线粒体分裂,从而调节子宫内膜基质细胞的凋亡和迁移。
这篇文章发表后,一位读者提请编辑注意,第 7804 页图 5A 中描绘的 Western 印迹分析实验的实验设计以及该图的整体组织可能存在缺陷,因为图中线粒体和细胞膜蛋白质仅有一组支持对照的 Western 印迹数据;在这种情况下,蛋白质必然需要在不同的实验中从两个不同的细胞样本中获得,并在不同的凝胶上印迹。此外,还有人担心某些凝胶的连续性/拼接事件可能会出现断裂,因此图中的蛋白质条带并不是连续显示的,因为它们本来就会出现在受影响的切片中。经过内部调查,《分子医学报告》编辑同意读者的观点,即图 5 的显示存在异常。因此,由于对所提供的数据缺乏信心,编辑决定将该文章撤稿。作者被要求解释这些问题,但编辑部没有收到回复。对于给读者带来的不便,编辑深表歉意,我们也感谢读者将此事告知我们。[Molecular Medicine Reports 17: 7797-7806, 2018; DOI: 10.3892/mmr.2018.8823]。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Molecular medicine reports
Molecular medicine reports 医学-病理学
CiteScore
7.60
自引率
0.00%
发文量
321
审稿时长
1.5 months
期刊介绍: Molecular Medicine Reports is a monthly, peer-reviewed journal available in print and online, that includes studies devoted to molecular medicine, underscoring aspects including pharmacology, pathology, genetics, neurosciences, infectious diseases, molecular cardiology and molecular surgery. In vitro and in vivo studies of experimental model systems pertaining to the mechanisms of a variety of diseases offer researchers the necessary tools and knowledge with which to aid the diagnosis and treatment of human diseases.
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