Research progress of biomarkers in evaluating the severity and prognostic value of severe pneumonia in children.

IF 2.1 3区 医学 Q2 PEDIATRICS
Frontiers in Pediatrics Pub Date : 2024-10-01 eCollection Date: 2024-01-01 DOI:10.3389/fped.2024.1417644
Weihua Gong, Kaijie Gao, Zhiming Shan, Liu Yang, Panpan Fang, Ci Li, Junmei Yang, Jiajia Ni
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引用次数: 0

Abstract

Pneumonia is a serious and common infectious disease in children. If not treated in time, it may develop into severe pneumonia. Severe pneumonia in children is mainly characterized by hypoxia and acidosis, often accompanied by various complications such as sepsis and multiple organ dysfunction. Severe pneumonia has a rapid onset and progression, and a high mortality rate. Biomarkers assist clinicians in the early diagnosis and treatment of patients by quickly and accurately identifying their conditions and prognostic risks. In this study, common clinical and novel biomarkers of severe pneumonia in children were reviewed, and the application value of biomarkers related to the severity and prognosis of severe pneumonia in children was evaluated to provide help for early identification and precise intervention by clinicians.

生物标志物在评估儿童重症肺炎严重程度和预后价值方面的研究进展。
肺炎是一种严重的儿童常见传染病。如不及时治疗,可能发展为重症肺炎。儿童重症肺炎主要表现为缺氧和酸中毒,常伴有各种并发症,如败血症和多器官功能障碍。重症肺炎起病急、病情发展快、死亡率高。生物标志物可以快速准确地识别患者的病情和预后风险,从而帮助临床医生对患者进行早期诊断和治疗。本研究综述了儿童重症肺炎常见的临床生物标志物和新型生物标志物,评估了与儿童重症肺炎严重程度和预后相关的生物标志物的应用价值,为临床医生早期识别和精确干预提供帮助。
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来源期刊
Frontiers in Pediatrics
Frontiers in Pediatrics Medicine-Pediatrics, Perinatology and Child Health
CiteScore
3.60
自引率
7.70%
发文量
2132
审稿时长
14 weeks
期刊介绍: Frontiers in Pediatrics (Impact Factor 2.33) publishes rigorously peer-reviewed research broadly across the field, from basic to clinical research that meets ongoing challenges in pediatric patient care and child health. Field Chief Editors Arjan Te Pas at Leiden University and Michael L. Moritz at the Children''s Hospital of Pittsburgh are supported by an outstanding Editorial Board of international experts. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. Frontiers in Pediatrics also features Research Topics, Frontiers special theme-focused issues managed by Guest Associate Editors, addressing important areas in pediatrics. In this fashion, Frontiers serves as an outlet to publish the broadest aspects of pediatrics in both basic and clinical research, including high-quality reviews, case reports, editorials and commentaries related to all aspects of pediatrics.
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