Electrophysiological measures of patients with unilateral spatial neglect after brain disease: A systematic review

IF 2.7 4区医学 Q3 NEUROSCIENCES

Brain Research Pub Date : 2024-10-17 DOI:10.1016/j.brainres.2024.149260

Zihan Yao, Guixiang Shan, Weiqun Song, Linlin Ye

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引用次数: 0

Abstract

Introduction

The investigation of brainwave changes during the recovery process of unilateral spatial neglect (USN) has garnered considerable attention in recent years. This paper presents an updated overview of the evolving brainwave patterns during USN rehabilitation, aiming to predict clinical outcomes and guide the selection of effective recovery strategies.

Methods

A systematic review was conducted, encompassing English literature published up to June 2024. Databases including PubMed, Web of Science, and clinical trials were utilized. The included studies assessed brainwaves using electroencephalography (EEG) in at least one group with USN. However, the diverse nature of these studies posed challenges for a quantitative synthesis.

Results

The final quantitative synthesis comprised 36 studies, incorporating a total of 4517 data points. The analysis revealed abnormalities in alpha, beta, and gamma brainwave activity, along with alterations in the functional monitoring of the alpha band during USN rehabilitation. Additionally, reductions were observed in specific brainwave components such as P1, N1, P2, P300, early directing attention negativity (EDAN), late directing attention positivity (LDAP), and contingent negative variation (CNV). However, findings regarding measures of synchrony, connectivity, and evoked responses across different frequency bands exhibited variability.

Conclusions

Various indicators of brainwave activity displayed changes at different stages of post-stroke neglect rehabilitation, highlighting the significance of neural network dysfunction in this process. Nonetheless, due to the diversity of the studies, further investigation is necessary to achieve a more comprehensive understanding in future research endeavors.

查看原文本刊更多论文

脑部疾病后单侧空间忽略患者的电生理测量：系统综述。

前言近年来，对单侧空间忽略（USN）康复过程中脑电波变化的研究引起了广泛关注。本文对单侧空间忽略康复过程中不断变化的脑电波模式进行了最新概述，旨在预测临床结果并指导选择有效的康复策略：本文对截至 2024 年 6 月发表的英文文献进行了系统综述。采用的数据库包括 PubMed、Web of Science 和临床试验。纳入的研究通过脑电图（EEG）对至少一组 USN 患者的脑电波进行了评估。然而，这些研究的多样性给定量综述带来了挑战：最终的定量综述包括 36 项研究，共纳入 4517 个数据点。分析结果显示，在 USN 康复过程中，阿尔法、贝塔和伽马脑电波活动出现异常，阿尔法波段的功能监测也发生了变化。此外，还观察到特定脑电波成分的减少，如 P1、N1、P2、P300、早期定向注意负性（EDAN）、晚期定向注意正性（LDAP）和或然性负变异（CNV）。然而，不同频段的同步性、连通性和诱发反应的测量结果却表现出差异性：结论：在脑卒中后忽视康复的不同阶段，脑电波活动的各种指标都发生了变化，这凸显了神经网络功能障碍在这一过程中的重要性。然而，由于研究的多样性，有必要在未来的研究工作中进行进一步调查，以获得更全面的认识。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Brain Research 医学-神经科学

CiteScore

5.90

自引率

3.40%

发文量

268

审稿时长

47 days

期刊介绍： An international multidisciplinary journal devoted to fundamental research in the brain sciences. Brain Research publishes papers reporting interdisciplinary investigations of nervous system structure and function that are of general interest to the international community of neuroscientists. As is evident from the journals name, its scope is broad, ranging from cellular and molecular studies through systems neuroscience, cognition and disease. Invited reviews are also published; suggestions for and inquiries about potential reviews are welcomed. With the appearance of the final issue of the 2011 subscription, Vol. 67/1-2 (24 June 2011), Brain Research Reviews has ceased publication as a distinct journal separate from Brain Research. Review articles accepted for Brain Research are now published in that journal.