Maternal adiposity measures and hypertensive disorders of pregnancy: a meta-analysis.

IF 2.8 2区医学 Q1 OBSTETRICS & GYNECOLOGY

BMC Pregnancy and Childbirth Pub Date : 2024-10-16 DOI:10.1186/s12884-024-06788-2

Caiping Xiang, Lun Sui, Xueteng Ding, Min Cao, Guoju Li, Zhanhui Du

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引用次数: 0

Abstract

Background: Hypertensive disorders of pregnancy (HDP) are a prevalent complication during pregnancy with significant implications for maternal and perinatal health globally. Maternal obesity is a known risk factor for HDP. This review sought to identify adiposity indicators in early pregnancy that are linked to the development of HDP.

Methods: We conducted a systematic search of the PubMed, Science Citation Index (Web of Science), and Embase databases. Screening and quality evaluation of studies was conducted independently by two reviewers. Both random effects meta-analysis and narrative synthesis were performed.

Results: Thirty-one studies were included with a pooled sample of 81,311 women. The meta-analysis showed that the odds of HDP were significantly increased by higher pregnancy measures of adiposity (pre-pregnancy body mass index (OR = 2.14, 95%CI: 1.67-2.75), visceral adipose tissue (OR = 1.79, 95%CI: 1.01-3.16), subcutaneous adiposity thickness (OR = 1.67, 95%CI: 1.36-2.05), waist circumference (OR = 2.20, 95%CI: 1.37-3.54), waist to-hip ratio (OR = 3.08, 95% CI: 1.38-6.87), weight gain (OR = 1.69, 95%CI: 1.42-2.02) and percentage body fat (OR = 1.71, 95%CI: 1.16-2.53)). Epicardial fat thickness was significantly associated with HDP, although limited data were available.

Conclusions: The results of our study highlight the importance of investigating the predictive value of adiposity measures in identifying the risk of HDP to tailor care towards women at the highest risk.

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孕产妇脂肪测量与妊娠高血压疾病：一项荟萃分析。

背景：妊娠期高血压疾病（HDP）是妊娠期的一种常见并发症，对全球孕产妇和围产期健康具有重大影响。孕产妇肥胖是妊娠高血压疾病的一个已知风险因素。本综述旨在确定与妊娠期高血压发病有关的孕早期肥胖指标：我们对 PubMed、科学引文索引（Web of Science）和 Embase 数据库进行了系统检索。研究的筛选和质量评估由两名审稿人独立完成。同时进行了随机效应荟萃分析和叙述性综合分析：共纳入 31 项研究，汇总样本为 81 311 名女性。荟萃分析表明，妊娠期脂肪含量越高（妊娠前体重指数（OR = 2.14，95%CI：1.67-2.75）、内脏脂肪组织（OR = 1.79，95%CI：1.01-3.16）、皮下脂肪含量（OR = 2.14，95%CI：1.67-2.75）），发生 HDP 的几率就会显著增加。16）、皮下脂肪厚度（OR = 1.67，95%CI：1.36-2.05）、腰围（OR = 2.20，95%CI：1.37-3.54）、腰臀比（OR = 3.08，95%CI：1.38-6.87）、体重增加（OR = 1.69，95%CI：1.42-2.02）和体脂百分比（OR = 1.71，95%CI：1.16-2.53））。心外膜脂肪厚度与 HDP 显著相关，但可用数据有限：我们的研究结果凸显了研究脂肪测量在识别 HDP 风险方面的预测价值的重要性，以便为高风险妇女提供量身定制的护理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMC Pregnancy and Childbirth OBSTETRICS & GYNECOLOGY-

CiteScore

4.90

自引率

6.50%

发文量

845

审稿时长

3-8 weeks

期刊介绍： BMC Pregnancy & Childbirth is an open access, peer-reviewed journal that considers articles on all aspects of pregnancy and childbirth. The journal welcomes submissions on the biomedical aspects of pregnancy, breastfeeding, labor, maternal health, maternity care, trends and sociological aspects of pregnancy and childbirth.