Association of CSF α-synuclein seed amplification assay positivity with disease progression and cognitive decline: A longitudinal Alzheimer's Disease Neuroimaging Initiative study

IF 13 1区医学 Q1 CLINICAL NEUROLOGY

Alzheimer's & Dementia Pub Date : 2024-10-20 DOI:10.1002/alz.14276

Duygu Tosun, Zachary Hausle, Pamela Thropp, Luis Concha-Marambio, Jennifer Lamoureux, Russ Lebovitz, Leslie M. Shaw, Andrew B. Singleton, Michael W. Weiner, , Cornelis Blauwendraat

引用次数: 0

Abstract

Cerebrospinal fluid (CSF) α-synuclein (α-syn) seed amplification assay (SAA) is a sensitive and specific tool for detecting Lewy body co-pathology in Alzheimer's disease.

查看原文本刊更多论文

脑脊液α-突触核蛋白种子扩增检测阳性与疾病进展和认知能力下降的关系：阿尔茨海默病神经影像学纵向研究

脑脊液（CSF）α-突触核蛋白（α-syn）种子扩增试验（SAA）是检测阿尔茨海默病路易体合并病理学的一种灵敏而特异的工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Alzheimer's & Dementia 医学-临床神经学

CiteScore

14.50

自引率

5.00%

发文量

299

审稿时长

3 months

期刊介绍： Alzheimer's & Dementia is a peer-reviewed journal that aims to bridge knowledge gaps in dementia research by covering the entire spectrum, from basic science to clinical trials to social and behavioral investigations. It provides a platform for rapid communication of new findings and ideas, optimal translation of research into practical applications, increasing knowledge across diverse disciplines for early detection, diagnosis, and intervention, and identifying promising new research directions. In July 2008, Alzheimer's & Dementia was accepted for indexing by MEDLINE, recognizing its scientific merit and contribution to Alzheimer's research.