Validity and Reliability of the Amharic Version of EORTC QLQ-OG25 Among Esophagogastric Cancer Patients in Ethiopia

IF 1.5 Q4 ONCOLOGY

Cancer reports Pub Date : 2024-10-18 DOI:10.1002/cnr2.70035

Lidya Genene Abebe, Abigiya Wondimagegnehu, Eva Johanna Kantelhardt, Adamu Addissie

{"title":"Validity and Reliability of the Amharic Version of EORTC QLQ-OG25 Among Esophagogastric Cancer Patients in Ethiopia","authors":"Lidya Genene Abebe, Abigiya Wondimagegnehu, Eva Johanna Kantelhardt, Adamu Addissie","doi":"10.1002/cnr2.70035","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Cancers of the stomach and esophagus are the fourth and sixth most common causes of cancer-related deaths worldwide, respectively. Although various tools have been developed to assess the quality of life of patients with esophagogastric cancer, EORTC QLQ-C30 and EORTC QLQ-OG25 are the most used all over the world. However, they have not been validated in an Ethiopian context. Therefore, this study aimed to evaluate the psychometric properties of EORTC QLQ-OG25 among Ethiopian patients with esophageal and gastric cancer.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>EORTC QLQ-OG25 is a 25-item tool with 10 single items and six symptom scales: Eating restrictions, reflux, dysphagia, odynophagia, discomfort and pain, and anxiety. The tool was translated into Amharic according to the EORTC forward-backward translation protocol. To check its validity and reliability, a cross-sectional study among 158 patients was conducted from March to May 2020 at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. The psychometric properties of EORTC QLQ-C30 and EORTC QLQ-OG25 were assessed using multitrait scale analysis, known group validity, convergent validity, and divergent validity. Internal consistency was examined with Cronbach's alpha.</p>\n </section>\n \n <section>\n \n <h3> Result</h3>\n \n <p>Eighty-three (52.5%) of the participants were men; the median age was 50 years (IQR = 18 years). The overall item correlation alpha values ranged between 0.39 and 0.7. All item correlations within their scales were greater than 0.4. The correlation coefficients between all items and their own domain were greater than for other domains. The esophagogastric and core questionnaire correlation ranged from −0.65 to 0.62. The tool showed a significant difference between patients with good physical function and those with impaired physical function.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>The findings suggest that the Amharic version of EORTC QLQ-OG25 is a valid and reliable tool among patients from Ethiopia with esophagus and gastric cancer. Therefore, we recommend that researchers and clinicians use the core tool together with the specific tool.</p>\n </section>\n </div>","PeriodicalId":9440,"journal":{"name":"Cancer reports","volume":null,"pages":null},"PeriodicalIF":1.5000,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cnr2.70035","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cancer reports","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/cnr2.70035","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ONCOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background

Cancers of the stomach and esophagus are the fourth and sixth most common causes of cancer-related deaths worldwide, respectively. Although various tools have been developed to assess the quality of life of patients with esophagogastric cancer, EORTC QLQ-C30 and EORTC QLQ-OG25 are the most used all over the world. However, they have not been validated in an Ethiopian context. Therefore, this study aimed to evaluate the psychometric properties of EORTC QLQ-OG25 among Ethiopian patients with esophageal and gastric cancer.

Methods

EORTC QLQ-OG25 is a 25-item tool with 10 single items and six symptom scales: Eating restrictions, reflux, dysphagia, odynophagia, discomfort and pain, and anxiety. The tool was translated into Amharic according to the EORTC forward-backward translation protocol. To check its validity and reliability, a cross-sectional study among 158 patients was conducted from March to May 2020 at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. The psychometric properties of EORTC QLQ-C30 and EORTC QLQ-OG25 were assessed using multitrait scale analysis, known group validity, convergent validity, and divergent validity. Internal consistency was examined with Cronbach's alpha.

Result

Eighty-three (52.5%) of the participants were men; the median age was 50 years (IQR = 18 years). The overall item correlation alpha values ranged between 0.39 and 0.7. All item correlations within their scales were greater than 0.4. The correlation coefficients between all items and their own domain were greater than for other domains. The esophagogastric and core questionnaire correlation ranged from −0.65 to 0.62. The tool showed a significant difference between patients with good physical function and those with impaired physical function.

Conclusions

The findings suggest that the Amharic version of EORTC QLQ-OG25 is a valid and reliable tool among patients from Ethiopia with esophagus and gastric cancer. Therefore, we recommend that researchers and clinicians use the core tool together with the specific tool.

查看原文本刊更多论文

埃塞俄比亚食管胃癌患者阿姆哈拉语版 EORTC QLQ-OG25 的有效性和可靠性

背景胃癌和食道癌分别是全球第四大和第六大癌症相关死亡原因。虽然已经开发了多种工具来评估食管胃癌患者的生活质量，但 EORTC QLQ-C30 和 EORTC QLQ-OG25 是全世界使用最多的工具。然而，它们尚未在埃塞俄比亚进行过验证。因此，本研究旨在评估 EORTC QLQ-OG25 在埃塞俄比亚食道癌和胃癌患者中的心理测量特性。方法 EORTC QLQ-OG25 是一个 25 个项目的工具，包括 10 个单项和 6 个症状量表：进食限制、反流、吞咽困难、吞咽困难、不适和疼痛以及焦虑。该工具根据 EORTC 前向-后向翻译协议翻译成阿姆哈拉语。为了检验该工具的有效性和可靠性，埃塞俄比亚亚的斯亚贝巴 Tikur Anbessa 专科医院于 2020 年 3 月至 5 月对 158 名患者进行了横断面研究。采用多特征量表分析、已知群体效度、收敛效度和发散效度评估了 EORTC QLQ-C30 和 EORTC QLQ-OG25 的心理测量特性。用 Cronbach's alpha 检验了内部一致性。结果 83 名参与者（52.5%）为男性，年龄中位数为 50 岁（IQR = 18 岁）。总体项目相关性α值介于 0.39 和 0.7 之间。量表内所有项目的相关系数均大于 0.4。所有项目与其自身领域的相关系数均大于其他领域。食管胃和核心问卷的相关系数在-0.65 到 0.62 之间。该工具显示，身体功能良好的患者与身体功能受损的患者之间存在明显差异。结论研究结果表明，在埃塞俄比亚的食道癌和胃癌患者中，阿姆哈拉语版 EORTC QLQ-OG25 是一种有效、可靠的工具。因此，我们建议研究人员和临床医生同时使用核心工具和特定工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Cancer reports Medicine-Oncology

CiteScore

2.70

自引率

5.90%

发文量

160

审稿时长

17 weeks