Where to start? Activity-dependent alternative translation initiation generates multifunctional proteoforms in the brain

IF 14.5 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Molecular Cell Pub Date : 2024-10-17 DOI:10.1016/j.molcel.2024.09.029

Adam Kosti, Gary J. Bassell

引用次数: 0

Abstract

In this issue of Molecular Cell, Lee et al.¹ report that alternative translation initiation can generate new proteoforms with distinct localization patterns in a neuronal activity-dependent manner.

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从哪里开始？活动依赖性替代翻译起始在大脑中产生多功能蛋白形式

在本期的《分子细胞》（Molecular Cell）杂志上，Lee 等人1 报告说，替代翻译起始能以神经元活动依赖的方式产生具有不同定位模式的新蛋白形式。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Molecular Cell 生物-生化与分子生物学

CiteScore

26.00

自引率

3.80%

发文量

389

审稿时长

1 months

期刊介绍： Molecular Cell is a companion to Cell, the leading journal of biology and the highest-impact journal in the world. Launched in December 1997 and published monthly. Molecular Cell is dedicated to publishing cutting-edge research in molecular biology, focusing on fundamental cellular processes. The journal encompasses a wide range of topics, including DNA replication, recombination, and repair; Chromatin biology and genome organization; Transcription; RNA processing and decay; Non-coding RNA function; Translation; Protein folding, modification, and quality control; Signal transduction pathways; Cell cycle and checkpoints; Cell death; Autophagy; Metabolism.