Role of KIM-1 in early diagnosis of contrast-induced nephropathy following invasive cardiac procedure: A systematic review

IF 2.3 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology and Global Health Pub Date : 2024-10-08 DOI:10.1016/j.cegh.2024.101765

Mantasha Shuaib , Md Masoom , Mohd Ashif Khan

引用次数: 0

Abstract

This systematic review aims to provide a comprehensive analysis of the diagnostic efficacy of KIM-1 in CI-AKI. We evaluated its potential as a robust biomarker for the early identification and prediction of AKI progression.

Methodology

To assess KIM-1 as a biomarker for CI-AKI, relevant databases were searched. Inclusion criteria comprised studies measuring KIM-1 levels in patients undergoing cardiac procedures with contrast media and data were extracted. Methodological quality and bias were evaluated using Quadas-2 tool.

Conclusion

KIM-1 shows promise as a biomarker for renal injury. Its upregulation, correlation with injury severity, and involvement in tissue repair support its clinical relevance.

Prospero registration number

CRD42023431419.

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KIM-1 在有创心脏手术后造影剂诱发肾病的早期诊断中的作用：系统综述

本系统综述旨在全面分析 KIM-1 在 CI-AKI 中的诊断功效。为了评估 KIM-1 作为 CI-AKI 生物标志物的潜力，我们检索了相关数据库。纳入标准包括在使用造影剂进行心脏手术的患者中测量 KIM-1 水平的研究，并提取数据。结论KIM-1有望成为肾损伤的生物标记物。KIM-1的上调、与损伤严重程度的相关性以及对组织修复的参与支持了其临床相关性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Epidemiology and Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

4.60

自引率

7.70%

发文量

218

审稿时长

66 days

期刊介绍： Clinical Epidemiology and Global Health (CEGH) is a multidisciplinary journal and it is published four times (March, June, September, December) a year. The mandate of CEGH is to promote articles on clinical epidemiology with focus on developing countries in the context of global health. We also accept articles from other countries. It publishes original research work across all disciplines of medicine and allied sciences, related to clinical epidemiology and global health. The journal publishes Original articles, Review articles, Evidence Summaries, Letters to the Editor. All articles published in CEGH are peer-reviewed and published online for immediate access and citation.