Integrate and conquer: pan-cancer proteogenomics uncovers cancer vulnerabilities and therapeutic opportunities

IF 40.8 1区医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Signal Transduction and Targeted Therapy Pub Date : 2024-10-15 DOI:10.1038/s41392-024-02009-6

Debomita Chakraborty, Rossana Romero, Krishnaraj Rajalingam

引用次数: 0

Abstract

In a recent article published in Cell by Savage et al., the authors developed a computational workflow for integrating multi-omics data from readily available public online databases to provide novel insights into the proteogenomic landscape of several types of cancers and reveal new druggable targets for drug development or repurposing.¹

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整合与征服：泛癌症蛋白质组学揭示癌症弱点和治疗机会

最近，Savage 等人在《细胞》（Cell）杂志上发表了一篇文章，作者开发了一种计算工作流程，用于整合来自现成公共在线数据库的多组学数据，从而对几种癌症的蛋白质基因组状况有了新的认识，并揭示了新的药物开发或再利用靶点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Signal Transduction and Targeted Therapy Biochemistry, Genetics and Molecular Biology-Genetics

CiteScore

44.50

自引率

1.50%

发文量

384

审稿时长

5 weeks

期刊介绍： Signal Transduction and Targeted Therapy is an open access journal that focuses on timely publication of cutting-edge discoveries and advancements in basic science and clinical research related to signal transduction and targeted therapy. Scope: The journal covers research on major human diseases, including, but not limited to: Cancer,Cardiovascular diseases,Autoimmune diseases,Nervous system diseases.