New on-site color test to discriminate cocaine and cathinone derivatives

IF 1.9 4区医学 Q2 MEDICINE, LEGAL

Science & Justice Pub Date : 2024-10-02 DOI:10.1016/j.scijus.2024.09.008

Yukika Sobue , Koki Hotoda , Ayumu Ishii , Kosuke Kusakabe , Jun Ohta , Ruriko Takahashi , Noriyuki Kato , Tomoaki Sugaya , Koji Ishihara

引用次数: 0

Abstract

Color tests are advantageous for the field detection of illicit drugs because of their simplicity, low cost, and rapidity. The Scott test has been widely used as a color test for cocaine; however, it has the disadvantage of reacting with cathinone derivatives. To develop a more discriminating field-testing procedure, we evaluated the Cupric Reducing Antioxidant Capacity (CUPRAC) and bicinchoninic acid (BCA) tests for cathinones, to discriminate between cocaine and cathinones. Although the BCA test has the drawback of recognizing sugars with reducing properties, this can be overcome by adding ethanol and filtering the sample before testing. Both tests successfully distinguished between cocaine and cathinone. The BCA test was superior in terms of the ease of visual discrimination, whereas the CUPRAC test had the disadvantage of a longer reaction time.

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用于鉴别可卡因和卡西酮衍生物的新型现场颜色检测法

颜色测试因其简单、低成本和快速而在现场检测非法药物方面具有优势。斯科特检测法已被广泛用作可卡因的颜色检测，但它的缺点是会与卡西酮衍生物发生反应。为了开发一种更具鉴别力的现场检测程序，我们评估了铜还原抗氧化能力（CUPRAC）和双钦酸（BCA）卡西酮检测法，以区分可卡因和卡西酮。虽然 BCA 检验有识别具有还原性的糖类的缺点，但可以通过在检验前添加乙醇和过滤样品来克服。两种检测方法都能成功区分可卡因和卡西酮。BCA 检验在视觉分辨的难易程度上更胜一筹，而 CUPRAC 检验的缺点是反应时间较长。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Science & Justice 医学-病理学

CiteScore

4.20

自引率

15.80%

发文量

审稿时长

81 days

期刊介绍： Science & Justice provides a forum to promote communication and publication of original articles, reviews and correspondence on subjects that spark debates within the Forensic Science Community and the criminal justice sector. The journal provides a medium whereby all aspects of applying science to legal proceedings can be debated and progressed. Science & Justice is published six times a year, and will be of interest primarily to practising forensic scientists and their colleagues in related fields. It is chiefly concerned with the publication of formal scientific papers, in keeping with its international learned status, but will not accept any article describing experimentation on animals which does not meet strict ethical standards. Promote communication and informed debate within the Forensic Science Community and the criminal justice sector. To promote the publication of learned and original research findings from all areas of the forensic sciences and by so doing to advance the profession. To promote the publication of case based material by way of case reviews. To promote the publication of conference proceedings which are of interest to the forensic science community. To provide a medium whereby all aspects of applying science to legal proceedings can be debated and progressed. To appeal to all those with an interest in the forensic sciences.