Comparative analysis of modulation transfer function in various intraocular lenses under normal, decentration, and tilt conditions

AJO International Pub Date : 2024-10-02 DOI:10.1016/j.ajoint.2024.100069

Andi Masdipa , Yuji Matsuda , Sachiko Kaidzu , Masaki Tanito

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Abstract

Purpose

This study aims to compare the modulation transfer function (MTF) of different intraocular lenses (IOLs) under normal, decentration, and tilt conditions to evaluate their optical performance.

Design

Experimental setting.

Methods

A total of 12 IOL models (+20 D diopter, n = 3 each) were measured for MTF using the OptiSpheric IOL system with a 3 mm aperture diameter at a water temperature of 35 °C. Measurements were made with a spatial frequency of 0 - 200 lp/mm at the normal, decentration of 0.5 mm, and tilt of 5° positions.

Results

The MTF values were significantly different between normal and decentration conditions for XY1A (monofocal, toric) (P = 0.03), Tecnis ZCB00V (P = 0.0009), and NS-60YG (P = 0.004). Differences were significant between normal and tilt conditions for MP70 (P = 0.009), XY1 (P = 0.0005), and Clareon (P = 0.049), and were significant between decentration and tilt conditions only for LentisComfort (bifocal) (P = 0.01). With normal condition, MTF of Eyhance DIB00V (extended depth of focus) showed significant differences with 11 other IOLs (P < 0.0001), while LentisComfort exhibited differences with 10 other IOLs (P < 0.0001) except for XY1A (P = 0.0002). Similarly, with decentration condition, Eyhance DIB00V differed significantly from 11 other IOLs (P < 0.0001). With tilt condition, Eyhance DIB00V showed significant differences with 10 other IOLs (P < 0.0001) except for LentisComfort, which itself differed significantly from 10 other IOLs (P < 0.0001).

Conclusions

In the experimental settings, while specialized IOLs can address specific visual issues, monofocal IOLs remain superior in terms of overall contrast transfer quality and resolution even in the implanted IOL position is not ideal. These results provide a basis for recommending the use of monofocal IOLs in cases where the anterior chamber depth and lens position are prone to instability, such as in eyes with weakened zonules or following glaucoma filtering surgery.

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正常、分散和倾斜条件下各种眼内透镜调制传递函数的比较分析

目的本研究旨在比较不同眼内人工晶体（IOL）在正常、分散和倾斜条件下的调制传递函数（MTF），以评估其光学性能。方法使用 OptiSpheric IOL 系统在 35 °C 水温下测量 12 个 IOL 模型（+20 D 屈光度，每个模型 n = 3）的 MTF，该系统的孔径为 3 mm。结果 XY1A（单焦散光）（P = 0.03）、Tecnis ZCB00V（P = 0.0009）和 NS-60YG（P = 0.004）的 MTF 值在正常和散光条件下有显著差异。MP70 (P = 0.009)、XY1 (P = 0.0005) 和 Clareon (P = 0.049) 在正常和倾斜条件下差异显著，而 LentisComfort（双焦点）仅在分散和倾斜条件下差异显著 (P = 0.01)。在正常条件下，Eyhance DIB00V（扩展焦距）的 MTF 与其他 11 种人工晶体有显著差异（P = 0.0001），而 LentisComfort 与其他 10 种人工晶体有差异（P = 0.0001），只有 XY1A 除外（P = 0.0002）。同样，在分散条件下，Eyhance DIB00V 与其他 11 种人工晶体存在显著差异（P < 0.0001）。在倾斜条件下，Eyhance DIB00V 与其他 10 种人工晶体有显著差异（P < 0.0001），但 LentisComfort 除外，它与其他 10 种人工晶体有显著差异（P < 0.0001）。这些结果为推荐在前房深度和人工晶体位置容易不稳定的情况下使用单焦点人工晶体提供了依据，例如在眼球结构弱化或青光眼滤过手术后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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AJO International

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