A low-cost electronic and optical system for magnetic hyperthermia experimental studies

IF 2.5 3区材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY

Journal of Magnetism and Magnetic Materials Pub Date : 2024-09-26 DOI:10.1016/j.jmmm.2024.172552

Yavuz Öztürk , Ali Altan Yılmaz , Yiğit Seymen , Coşkun Harmanşah

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引用次数: 0

Abstract

Magnetic hyperthermia is an alternative to treatments such as chemotherapy and radiotherapy that employs the heat generated by magnetic nanoparticles under the influence of a magnetic field to kill cancer cells while ideally causing no harm to healthy tissues. A low-cost magnetic hyperthermia investigation platform with commercially available and easy-to-assemble parts was presented to provide and expand research in this area for a larger scientific community. The magnetic hyperthermia measurement system consists of three main parts: a designed thermally insulated sample holder, a commercial 88 kHz magnetic induction heater, and a custom-built fiber optic based refractometer as temperature sensor. The system was tested with commercial EFH-1 magnetic fluids. Time dependent temperature changes were measured for applied magnetic fields of 3.5 kA/m, 4.8 kA/m, and 6.0 kA/m. The corresponding specific loss power values were calculated as 0.28 W/g, 0.51 W/g, and 0.79 W/g, respectively. Intrinsic loss power of commercial ferrofluid was determined as 0.25 ± 0.01 nHm²/kg, found to be comparable to the results of specialized commercial magnetic hyperthermia systems. The results show that the system can easily be used for hyperthermia demonstrations for educational purposes as well as in convenient scientific research with proper calibration.

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用于磁热效应实验研究的低成本电子和光学系统

磁性热疗是化疗和放疗等治疗方法的替代疗法，它利用磁性纳米粒子在磁场影响下产生的热量杀死癌细胞，同时最好不会对健康组织造成伤害。为了向更多的科学界提供并扩大这一领域的研究，我们展示了一个低成本的磁热效应研究平台，其部件可在市场上买到，且易于组装。磁性热疗测量系统由三个主要部分组成：设计的隔热样品架、商用 88 kHz 磁感应加热器和定制的光纤折射仪作为温度传感器。该系统使用商用 EFH-1 磁性流体进行了测试。在 3.5 kA/m、4.8 kA/m 和 6.0 kA/m 的应用磁场下测量了随时间变化的温度。计算得出相应的比损耗功率值分别为 0.28 W/g、0.51 W/g 和 0.79 W/g。商用铁流体的本征损耗功率被测定为 0.25 ± 0.01 nHm2/kg，与专业商用磁热系统的结果相当。结果表明，该系统可轻松用于教育目的的热疗演示，也可在适当校准的情况下用于方便的科学研究。

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来源期刊

Journal of Magnetism and Magnetic Materials 物理-材料科学：综合

CiteScore

5.30

自引率

11.10%

发文量

1149

审稿时长

59 days

期刊介绍： The Journal of Magnetism and Magnetic Materials provides an important forum for the disclosure and discussion of original contributions covering the whole spectrum of topics, from basic magnetism to the technology and applications of magnetic materials. The journal encourages greater interaction between the basic and applied sub-disciplines of magnetism with comprehensive review articles, in addition to full-length contributions. In addition, other categories of contributions are welcome, including Critical Focused issues, Current Perspectives and Outreach to the General Public. Main Categories: Full-length articles: Technically original research documents that report results of value to the communities that comprise the journal audience. The link between chemical, structural and microstructural properties on the one hand and magnetic properties on the other hand are encouraged. In addition to general topics covering all areas of magnetism and magnetic materials, the full-length articles also include three sub-sections, focusing on Nanomagnetism, Spintronics and Applications. The sub-section on Nanomagnetism contains articles on magnetic nanoparticles, nanowires, thin films, 2D materials and other nanoscale magnetic materials and their applications. The sub-section on Spintronics contains articles on magnetoresistance, magnetoimpedance, magneto-optical phenomena, Micro-Electro-Mechanical Systems (MEMS), and other topics related to spin current control and magneto-transport phenomena. The sub-section on Applications display papers that focus on applications of magnetic materials. The applications need to show a connection to magnetism. Review articles: Review articles organize, clarify, and summarize existing major works in the areas covered by the Journal and provide comprehensive citations to the full spectrum of relevant literature.