Study Protocol and Mission for the Tohoku Registry of Acute Aortic Dissection (TRAD).

Circulation reports Pub Date : 2024-09-13 eCollection Date: 2024-10-10 DOI:10.1253/circrep.CR-24-0079
Kota Itagaki, Shintaro Katahira, Konosuke Sasaki, Midori Miyatake, Koki Ito, Kiichiro Kumagai, Norihiro Kondo, Shinya Masuda, Daichi Takagi, Azuma Tabayashi, Keisuke Kanda, Ai Ishizawa, Atsushi Yamashita, Cholsu Kim, Shunsuke Kawamoto, Masaaki Naganuma, Keiichi Ishida, Kyohei Ueno, Yoshikatsu Saiki
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Abstract

Background: Acute aortic dissection (AAD) is a life-threatening condition that imposes a significant socioeconomic burden on society. The Tohoku Registry of Acute Aortic Dissection (TRAD) is a collaboration of 13 tertiary referral hospitals in the Tohoku region of Japan designed to investigate all aspects of AAD treatment in this district, and to address significant clinical questions to help understand its dynamic pathology and develop optimal strategies for treating AAD.

Methods and results: Comprehensive cases developing type A and type B AAD, including those with prehospital cardiopulmonary arrest transported to TRAD centers, over 5 years from 2017 to 2022 are registered. The TRAD dataset encompasses prehospital information, diagnostic imaging findings, treatment modalities, and outcomes for each case. After discharge, patients will be followed up for 10 years for survival, aortic events and inspection data.

Conclusions: We believe that this multicenter registry of AAD analyses will clarify the current short-term outcomes of recent surgical, endovascular, and medical treatments in the Tohoku region, and provide insights into the long-term outcomes of different treatment modalities to achieve extended life expectancy in reasonably good health.

东北急性主动脉夹层登记处(TRAD)的研究计划和任务。
背景:急性主动脉夹层(AAD)是一种危及生命的疾病,给社会造成了巨大的社会经济负担。东北急性主动脉夹层登记处(TRAD)是由日本东北地区的 13 家三级转诊医院合作建立的,旨在调查该地区 AAD 治疗的方方面面,解决重大临床问题,以帮助了解其动态病理,并制定治疗 AAD 的最佳策略:登记2017年至2022年5年间发生A型和B型AAD的综合病例,包括送往TRAD中心的院前心肺骤停患者。TRAD 数据集包括每个病例的院前信息、影像诊断结果、治疗方式和结果。出院后,将对患者进行为期 10 年的生存、主动脉事件和检查数据随访:我们相信,这项多中心 AAD 分析登记将明确东北地区近期手术、血管内治疗和内科治疗的短期疗效,并为不同治疗方式的长期疗效提供见解,以实现在合理健康状况下延长预期寿命。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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