Study protocol for a single-arm pilot trial investigating the feasibility of a multimodal digital technology for managing metabolic syndrome in patients with chronic obstructive pulmonary disease

IF 4.2 3区生物学 Q1 BIOCHEMICAL RESEARCH METHODS

Methods Pub Date : 2024-10-09 DOI:10.1016/j.ymeth.2024.10.003

Bruna R. da Silva , Amanda I. Radil , Liam Collins , Nathanial Maeda , Carla M. Prado , Martin Ferguson-Pell , Doug Klein

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引用次数: 0

Abstract

Individuals diagnosed with Chronic Obstructive Pulmonary Disease (COPD) are exposed to an increased risk of metabolic syndrome (MetS), which negatively affects their health outcomes and quality of life. Lifestyle interventions have shown promise in managing MetS. This study outlines the protocol for a web-based multimodal self-care program, Digital Metabolic Rehabilitation, for managing MetS in patients with COPD. The Digital Metabolic Rehabilitation is a single-arm pilot trial that integrates the Canadian Health Advanced by Nutrition and Graded Exercise (CHANGE) Program and a web-based wellness platform. The web-based wellness platform employed in this study is My Viva Plan (MVP)®, which integrates a holistic, multicomponent approach to promote wellness. The intervention will primarily focus on lifestyle changes for patients with COPD. Over 6 months, participants will use the web-based wellness platform and engage in weekly online support group sessions. Fifty patients diagnosed with stage I-II COPD and MetS will participate. Blood tests, anthropometrics, body composition, physical function, muscle strength, physical activity, energy metabolism, quality of life and mental health will be assessed at baseline, 3, and 6 months. The Digital Metabolic Rehabilitation program aims to explore whether a multimodal integrative intervention delivered through a web-based wellness platform can be implemented by patients with COPD with MetS. By combining the expertise of the CHANGE Program with the digital delivery format, the intervention seeks to enhance self-monitoring and foster better self-management practices. The protocol outlines a novel and potentially impactful intervention for managing MetS in patients with COPD.

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慢性阻塞性肺病患者代谢综合征管理多模式数字技术可行性单臂试点试验研究方案。

被诊断为慢性阻塞性肺病（COPD）的患者患代谢综合征（MetS）的风险增加，这对他们的健康状况和生活质量产生了负面影响。生活方式干预对控制代谢综合征很有帮助。本研究概述了基于网络的多模式自我保健计划 "数字代谢康复 "的方案，用于控制慢性阻塞性肺病患者的代谢综合征。数字代谢康复是一项单臂可行性试验，它整合了加拿大营养和分级运动健康高级计划（CHANGE）和基于网络的健康平台。本研究采用的网络健康平台是 "我的万岁计划"（MVP）®，它整合了一种促进健康的整体、多成分方法。干预措施将主要侧重于慢性阻塞性肺病患者生活方式的改变。在 6 个月的时间里，参与者将使用基于网络的健康平台，并参加每周一次的在线支持小组会议。50 名被诊断为 I-II 期慢性阻塞性肺病和 MetS 的患者将参与其中。将在基线、3 个月和 6 个月时对血液检测、人体测量、身体成分、身体功能、肌肉力量、体力活动、能量代谢、生活质量和心理健康进行评估。数字代谢康复计划旨在探索慢性阻塞性肺病合并代谢综合征患者能否通过网络健康平台实施多模式综合干预。通过将 "改变 "计划的专业知识与数字交付形式相结合，该干预措施旨在加强自我监测，促进更好的自我管理实践。该方案概述了一种管理慢性阻塞性肺病患者 MetS 的新颖且具有潜在影响力的干预措施。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Methods 生物-生化研究方法

CiteScore

9.80

自引率

2.10%

发文量

222

审稿时长

11.3 weeks

期刊介绍： Methods focuses on rapidly developing techniques in the experimental biological and medical sciences. Each topical issue, organized by a guest editor who is an expert in the area covered, consists solely of invited quality articles by specialist authors, many of them reviews. Issues are devoted to specific technical approaches with emphasis on clear detailed descriptions of protocols that allow them to be reproduced easily. The background information provided enables researchers to understand the principles underlying the methods; other helpful sections include comparisons of alternative methods giving the advantages and disadvantages of particular methods, guidance on avoiding potential pitfalls, and suggestions for troubleshooting.