Surface Roughness Examination of Glass Ionomer Restorative Cements Treated with Acidic and Basic Pediatric Medications: An In Vitro Study.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-08-27 eCollection Date: 2024-07-01 DOI:10.4103/jispcd.jispcd_212_23

Zainab R Hasan, Noor R Al-Hasani, Ali I Ibrahim

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引用次数: 0

Abstract

Background: Consumption of different types of beverages and liquid drugs can affect of the surface properties of restorative material. This may lead to an increased probability of dental caries and periodontal inflammation.

Aim: This study evaluated and compared the effect of amoxicillin suspension (AMS) and azithromycin suspension (AZS) on the surface roughness (SR) of silver-reinforced glass ionomer (SGI) and nano resin-modified glass ionomer (NGI).

Material and methods: Thirty disks (2 mm height × 4 mm diameter) of each glass ionomer (GI) type were prepared and subdivided into three groups (n = 10), which were separately exposed to AMS, AZS, and artificial saliva (AS). SR was evaluated by atomic force microscopy before and after three-immersion protocols repeated over a 3-week duration with 2-day intervals. In each protocol, the GI samples were exposed weekly to AMS three times daily, AZS once daily, and a full day to AS.

Results: This study demonstrated, for the first time, the effect of a basic drug (AZS) on the SR of GIs. Intra- and inter-group comparisons showed significant changes (P ˂ 0.05) in the SR pattern of the GIs after immersion cycles in AZS, AMS, and AS. However, the acidic medication (AMS) exhibited significantly higher changes in SGI than in NGI.

Conclusions: The SR of NGIs and SGIs can be significantly affected by the use of AMS and AZS suspensions. SGI demonstrated higher SR deterioration than NGI after immersion cycles in AMS.

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用酸性和碱性儿科药物处理的玻璃离子树脂修复体的表面粗糙度检查：体外研究。

背景：饮用不同类型的饮料和液体药物会影响修复材料的表面特性。目的：本研究评估并比较了阿莫西林悬浮液（AMS）和阿奇霉素悬浮液（AZS）对银增强玻璃离子膜（SGI）和纳米树脂改性玻璃离子膜（NGI）表面粗糙度（SR）的影响：制备每种玻璃离子膜（GI）类型的 30 个圆盘（高 2 mm × 直径 4 mm），并将其分成三组（n = 10），分别暴露于 AMS、AZS 和人工唾液（AS）中。在为期 3 周、间隔 2 天的三次浸泡过程前后，用原子力显微镜对 SR 进行了评估。在每个方案中，胃肠道样本每周暴露于 AMS 中，每天三次；每天暴露于 AZS 中，一次；全天暴露于 AS 中：这项研究首次证明了一种基本药物（AZS）对胃肠道样本 SR 的影响。组内和组间比较显示，在浸泡 AZS、AMS 和 AS 周期后，胃肠道 SR 模式发生了显著变化（P ˂ 0.05）。然而，酸性药物（AMS）在 SGI 中的变化明显高于 NGI：结论：使用 AMS 和 AZS 悬浮液会严重影响 NGI 和 SGI 的 SR。在 AMS 中浸泡循环后，SGI 比 NGI 的 SR 退化程度更高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.